UniProt Q9NVH0
Exonuclease 3'-5' domain-containing protein 2 (Q9NVH0)
Exonuclease 3'-5' domain-containing protein 2 (UniProt Q9NVH0), EC 3.1.11.1: 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9NVH0
- Protein
- Exonuclease 3'-5' domain-containing protein 2
- EC
- 3.1.11.1
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 3 records with a druggable one
Structures
17 records of Q9NVH0 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K17 | Crystal structure of EXD2 exonuclease domain | x-ray diffraction | A, B | NA | 2 (best 0.42) |
| 6K17 | Crystal structure of EXD2 exonuclease domain | x-ray diffraction | A, B | NA | — |
| 6K18 | Crystal structure of EXD2 exonuclease domain soaked in Mn | x-ray diffraction | A, B | MN | 4 (best 0.46) |
| 6K18 | Crystal structure of EXD2 exonuclease domain soaked in mn | x-ray diffraction | A, B | MN | — |
| 6K19 | Crystal structure of EXD2 exonuclease domain soaked in Mg | x-ray diffraction | A, B | MG | — |
| 6K19 | Crystal structure of EXD2 exonuclease domain soaked in mg | x-ray diffraction | A, B | MG | — |
| 6K1A | Crystal structure of EXD2 exonuclease domain soaked in Mn and Mg | x-ray diffraction | A, B | MN, MG | 3 (best 0.55) |
| 6K1A | Crystal structure of EXD2 exonuclease domain soaked in mn and mg | x-ray diffraction | A, B | MN, MG | — |
| 6K1B | Crystal structure of EXD2 exonuclease domain soaked in Mn and dGMP | x-ray diffraction | A, B | MN | 3 (best 0.51) |
| 6K1B | Crystal structure of EXD2 exonuclease domain soaked in mn and dgmp | x-ray diffraction | A, B | MN | — |
| 6K1C | Crystal structure of EXD2 exonuclease domain soaked in Mg and dGMP | x-ray diffraction | A, B | MG | 2 (best 0.42) |
| 6K1C | Crystal structure of EXD2 exonuclease domain soaked in mg and dgmp | x-ray diffraction | A, B | MG | — |
| 6K1D | Crystal structure of EXD2 exonuclease domain soaked in Mn and GMP | x-ray diffraction | A, B | MN | 7 (best 0.70) |
| 6K1D | Crystal structure of EXD2 exonuclease domain soaked in mn and gmp | x-ray diffraction | A, B | MN | — |
| 6K1E | Crystal structure of EXD2 exonuclease domain soaked in Mg and GMP | x-ray diffraction | A, B | MG | 5 (best 0.44) |
| 6K1E | Crystal structure of EXD2 exonuclease domain soaked in mg and gmp | x-ray diffraction | A, B | MG | — |
| Q9NVH0 | AlphaFold monomer V2.0 prediction for exonuclease 3'-5' domain- containing protein 2 (Q9NVH0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6K17 chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.75 Å
- 6K17 chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.75 Å
- 6K1B chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.94 Å
- 6K1B chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.94 Å
- 6K19 chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.91 Å
- 6K19 chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.91 Å
- 6K1C chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.69 Å
- 6K1C chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.69 Å
- 6K1E chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.97 Å
- 6K1E chain B against the predicted model Q9NVH0: TM-score 0.61, RMSD 1.97 Å
Elsewhere
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