UniProt Q9NV88
Integrator complex subunit 9 (Q9NV88)
Integrator complex subunit 9 (UniProt Q9NV88): 17 experimental structures and 1 predicted model on GenesisL1, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NV88
- Protein
- Integrator complex subunit 9
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 54 · 11 records with a druggable one
Structures
18 records of Q9NV88 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V8W | Crystal structure of human Integrator IntS9-IntS11 CTD complex | x-ray diffraction | A, C, E, G | — | 5 (best 0.67) |
| 5V8W | Crystal structure of human integrator INTS9-INTS11 ctd complex | x-ray diffraction | A, C, E, G | — | — |
| 7BFP | Structure of the Integrator cleavage module with INTS4/9/11 | electron microscopy | A | — | 9 (best 0.82) |
| 7BFP | Structure of the integrator cleavage module with INTS4/9/11 | electron microscopy | A | — | — |
| 7BFQ | Structure of the Integrator cleavage module with extended INTS4 and rigid body docked INTS9/11 CTD | electron microscopy | A | — | 9 (best 0.79) |
| 7BFQ | Structure of the integrator cleavage module with extended INTS4 and rigid body docked INTS9/11 ctd | electron microscopy | A | — | — |
| 7CUN | The structure of human Integrator-PP2A complex | electron microscopy | I | — | — |
| 7CUN | The structure of human integrator-PP2A complex | electron microscopy | I | — | — |
| 7PKS | Structural basis of Integrator-mediated transcription regulation | electron microscopy | i | — | 2 (best 0.82) |
| 7YCX | The structure of INTAC-PEC complex | electron microscopy | I | — | 1 (best 0.83) |
| 8R22 | INTS9-INTS11-BRAT1-WDR73 complex | electron microscopy | B | — | 6 (best 0.81) |
| 8R23 | INTS9-INTS11-BRAT1 complex | electron microscopy | B | — | 6 (best 0.79) |
| 8R2D | Integrator cleavage module assembly intermediate | electron microscopy | B | — | 6 (best 0.82) |
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | i | — | — |
| 8RBZ | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | electron microscopy | i | — | 3 (best 0.83) |
| 8RC4 | Structure of Integrator-PP2A complex | electron microscopy | i | — | 3 (best 0.86) |
| 8UIB | Structure of the human INTS9-INTS11-BRAT1 complex | electron microscopy | I | — | 4 (best 0.83) |
| Q9NV88 | AlphaFold monomer V2.0 prediction for integrator complex subunit 9 (Q9NV88) | predicted | A | — | — |
Experiment against prediction
- 8R2D chain B against the predicted model Q9NV88: TM-score 0.99, RMSD 0.90 Å
- 7PKS chain i against the predicted model Q9NV88: TM-score 0.98, RMSD 1.07 Å
- 8R23 chain B against the predicted model Q9NV88: TM-score 0.98, RMSD 0.96 Å
- 8R22 chain B against the predicted model Q9NV88: TM-score 0.98, RMSD 1.07 Å
- 8UIB chain I against the predicted model Q9NV88: TM-score 0.98, RMSD 1.02 Å
- 7BFP chain A against the predicted model Q9NV88: TM-score 0.97, RMSD 1.28 Å
- 7BFP chain A against the predicted model Q9NV88: TM-score 0.97, RMSD 1.28 Å
- 5V8W chain G against the predicted model Q9NV88: TM-score 0.93, RMSD 0.92 Å
- 8RBX chain i against the predicted model Q9NV88: TM-score 0.91, RMSD 2.63 Å
- 8RC4 chain i against the predicted model Q9NV88: TM-score 0.91, RMSD 2.61 Å
Elsewhere
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