UniProt Q9NUY8
TBC1 domain family member 23 (Q9NUY8)
TBC1 domain family member 23 (UniProt Q9NUY8): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NUY8
- Protein
- TBC1 domain family member 23
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 4 records with a druggable one
Structures
7 records of Q9NUY8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JL7 | crystal structure of TBC1D23 N terminal domain | x-ray diffraction | A | — | 6 (best 0.67) |
| 6JL7 | Crystal structure of TBC1D23 N terminal domain | x-ray diffraction | A | — | — |
| 6JM5 | Crystal structure of TBC1D23 C terminal domain | x-ray diffraction | A, B | NA | 2 (best 0.71) |
| 6JM5 | Crystal structure of TBC1D23 C terminal domain | x-ray diffraction | A, B | NA | — |
| 8JJ9 | Human FAM91A1 N terminal domain in complex with TBC1D23 | x-ray diffraction | C, D | — | 2 (best 0.48) |
| 8QQF | TBC1D23 PH domain complexed with STX16 TLY motif | x-ray diffraction | A, C | PO4 | 3 (best 0.63) |
| Q9NUY8 | AlphaFold monomer V2.0 prediction for TBC1 domain family member 23 (Q9NUY8) | predicted | A | — | 9 (best 0.72) |
Ligands
Experiment against prediction
- 6JL7 chain A against the predicted model Q9NUY8: TM-score 0.99, RMSD 0.62 Å
- 6JL7 chain A against the predicted model Q9NUY8: TM-score 0.99, RMSD 0.62 Å
- 6JM5 chain B against the predicted model Q9NUY8: TM-score 0.96, RMSD 1.31 Å
- 6JM5 chain B against the predicted model Q9NUY8: TM-score 0.96, RMSD 1.31 Å
- 8QQF chain C against the predicted model Q9NUY8: TM-score 0.95, RMSD 1.12 Å
- 6JM5 chain A against the predicted model Q9NUY8: TM-score 0.95, RMSD 1.06 Å
- 6JM5 chain A against the predicted model Q9NUY8: TM-score 0.95, RMSD 1.06 Å
- 8QQF chain A against the predicted model Q9NUY8: TM-score 0.94, RMSD 1.28 Å
- 8JJ9 chain D against the predicted model Q9NUY8: TM-score 0.18, RMSD 3.41 Å
- 8JJ9 chain C against the predicted model Q9NUY8: TM-score 0.17, RMSD 2.52 Å
Elsewhere
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