UniProt Q9NSU2
Three-prime repair exonuclease 1 (Q9NSU2)
Three-prime repair exonuclease 1 (UniProt Q9NSU2), EC 3.1.11.2: 9 experimental structures on GenesisL1, 6 ligands bound, 42 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9NSU2
- Protein
- Three-prime repair exonuclease 1
- EC
- 3.1.11.2
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 42 · 2 records with a druggable one
Structures
9 records of Q9NSU2 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7TQN | Structure of human TREX1 | x-ray diffraction | A | — | 1 (best 0.48) |
| 7TQN | Structure of human TREX1 | x-ray diffraction | A | — | — |
| 7TQO | Structure of human TREX1 | x-ray diffraction | A | — | 1 (best 0.45) |
| 7TQO | Structure of human TREX1 | x-ray diffraction | A | — | — |
| 7TQP | Structure of human TREX1 | x-ray diffraction | A | SO4 | — |
| 7TQQ | Structure of human TREX1-DNA complex | x-ray diffraction | A, B, E, F | — | — |
| 8VL7 | Co-crystal structure of human TREX1 in complex with an inhibitor | x-ray diffraction | A, B, C, D, E, F, G, H | A1ACJ, MG, UNX | 20 (best 0.64) |
| 9AVA | Co-crystal structure of human TREX1 in complex with an inhibitor | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | K, A1AG1, UNX | 20 (best 0.84) |
| Q9NSU2 | AlphaFold monomer V2.0 prediction for three-prime repair exonuclease 1 (Q9NSU2) | — | — | — |
Ligands
- UNX · Unknown atom or ion · in 2 records
- A1ACJ · (2P)-2-[3-bromo-2-(2-hydroxyethoxy)phenyl]-5-hydroxy-1-methyl-N-(1,2-oxazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide · in 1 record
- A1AG1 · (2R)-2-[(5R,6S,8R,9aS)-8-amino-1-oxo-5-(2-phenylethyl)hexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl]-N-[(3,4-dichlorophenyl)methyl]-4-methylpentanamide · in 1 record
- K · Potassium ion · in 1 record
- MG · Magnesium ion · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.