UniProt Q9NS69
Mitochondrial import receptor subunit TOM22 homolog (Q9NS69)
Mitochondrial import receptor subunit TOM22 homolog (UniProt Q9NS69): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 38 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NS69
- Protein
- Mitochondrial import receptor subunit TOM22 homolog
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 38 · 7 records with a druggable one
Structures
12 records of Q9NS69 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CK6 | Protein translocase of mitochondria | electron microscopy | C, D | PC1 | 5 (best 0.85) |
| 7CK6 | Protein translocase of mitochondria | electron microscopy | C, D | PC1 | — |
| 7CP9 | Cryo-EM structure of human mitochondrial translocase TOM complex at 3.0 angstrom. | electron microscopy | G, H | PC1 | 4 (best 0.86) |
| 7CP9 | Cryo-EM structure of human mitochondrial translocase tom complex at 3.0 ångström. | electron microscopy | G, H | PC1 | — |
| 7VBY | Tom core complex with Tom20 and Tom22 subunits. | electron microscopy | H, C | PC1 | 8 (best 0.86) |
| 7VC4 | Tom complex with Tom22 and Tom20 subunits | electron microscopy | C, H | — | 6 (best 0.87) |
| 7VD2 | Human TOM complex without cross-linking | electron microscopy | H, C | PC1 | 8 (best 0.86) |
| 7VD2 | Human tom complex without cross-linking | electron microscopy | H, C | PC1 | — |
| 7VDD | Human TOM complex with cross-linking | electron microscopy | C, H | — | 6 (best 0.86) |
| 7VDD | Human tom complex with cross-linking | electron microscopy | C, H | — | — |
| 8XVA | Human TOM complex with whole Tom20 | electron microscopy | C, H | — | 1 (best 0.74) |
| Q9NS69 | AlphaFold monomer V2.0 prediction for mitochondrial import receptor subunit TOM22 homolog (Q9NS69) | predicted | A | — | — |
Ligands
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 7 records
Experiment against prediction
- 7VBY chain C against the predicted model Q9NS69: TM-score 0.71, RMSD 2.31 Å
- 7VD2 chain C against the predicted model Q9NS69: TM-score 0.70, RMSD 2.32 Å
- 7VD2 chain C against the predicted model Q9NS69: TM-score 0.70, RMSD 2.32 Å
- 8XVA chain C against the predicted model Q9NS69: TM-score 0.69, RMSD 2.51 Å
- 7VBY chain H against the predicted model Q9NS69: TM-score 0.68, RMSD 2.25 Å
- 7CK6 chain C against the predicted model Q9NS69: TM-score 0.68, RMSD 1.98 Å
- 7CK6 chain C against the predicted model Q9NS69: TM-score 0.68, RMSD 1.98 Å
- 7VD2 chain H against the predicted model Q9NS69: TM-score 0.67, RMSD 2.28 Å
- 7VD2 chain H against the predicted model Q9NS69: TM-score 0.67, RMSD 2.28 Å
- 8XVA chain H against the predicted model Q9NS69: TM-score 0.65, RMSD 2.64 Å
Elsewhere
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