UniProt Q9NRA2
Sialin (Q9NRA2)
Sialin (UniProt Q9NRA2): 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NRA2
- Protein
- Sialin
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 24 · 8 records with a druggable one
Structures
8 records of Q9NRA2 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8DWI | Molecular Mechanism of Sialic Acid Transport Mediated by Sialin | electron microscopy | A | — | 4 (best 0.78) |
| 8U3D | Structure of Apo Sialin at pH7.5 | electron microscopy | A | — | 2 (best 0.78) |
| 8U3E | Structure of Apo Sialin at pH5.0 | electron microscopy | A | — | 2 (best 0.78) |
| 8U3F | Structure of Apo Sialin R168K mutant | electron microscopy | A | — | 2 (best 0.80) |
| 8U3G | Structure of NAAG-bound Sialin | electron microscopy | A | ACE | 3 (best 0.71) |
| 8U3H | Structure of Fmoc-Leu-OH bound Sialin | electron microscopy | A | VP1, LEU | 3 (best 0.79) |
| 9AYB | Structure of Apo Sialin S61A mutant | electron microscopy | A | — | 2 (best 0.82) |
| Q9NRA2 | AlphaFold monomer V2.0 prediction for sialin (Q9NRA2) | predicted | A | — | 6 (best 0.81) |
Ligands
Experiment against prediction
- 8U3F chain A against the predicted model Q9NRA2: TM-score 0.98, RMSD 1.17 Å
- 9AYB chain A against the predicted model Q9NRA2: TM-score 0.98, RMSD 1.21 Å
- 8U3H chain A against the predicted model Q9NRA2: TM-score 0.85, RMSD 3.33 Å
- 8U3G chain A against the predicted model Q9NRA2: TM-score 0.85, RMSD 3.17 Å
- 8U3D chain A against the predicted model Q9NRA2: TM-score 0.84, RMSD 3.34 Å
- 8U3E chain A against the predicted model Q9NRA2: TM-score 0.84, RMSD 3.38 Å
- 8DWI chain A against the predicted model Q9NRA2: TM-score 0.84, RMSD 3.48 Å
Elsewhere
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