UniProt Q9NR30
Nucleolar RNA helicase 2 (Q9NR30)
Nucleolar RNA helicase 2 (UniProt Q9NR30), EC 3.6.4.13: 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NR30
- Protein
- Nucleolar RNA helicase 2
- EC
- 3.6.4.13
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 2 · 0 records with a druggable one
Structures
8 records of Q9NR30 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M3D | NMR structure of the GUCT domain from human DEAD box polypeptide 21 | solution nmr | A | — | — |
| 2M3D | NMR structure of the guct domain from human dead box polypeptide 21 | solution nmr | A | — | — |
| 6L5L | Crystal structure of human dead-box RNA helicase DDX21 at apo state | x-ray diffraction | A | MG | — |
| 6L5M | Crystal structure of human dead-box RNA helicase DDX21 in complex with AMP | x-ray diffraction | A, B, C, D, E | AMP | — |
| 6L5N | Crystal structure of human dead-box RNA helicase DDX21 at post-unwound state | x-ray diffraction | A, B | ANP, MG | — |
| 6L5O | Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state | x-ray diffraction | A | ADP, MG | 2 (best 0.36) |
| 6L5O | Crystal structure of human dead-box RNA helicase DDX21 at post- hydrolysis state | x-ray diffraction | A | ADP, MG | — |
| Q9NR30 | AlphaFold monomer V2.0 prediction for nucleolar RNA helicase 2 (Q9NR30) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6L5N chain A against the predicted model Q9NR30: TM-score 0.98, RMSD 1.11 Å
- 6L5N chain B against the predicted model Q9NR30: TM-score 0.97, RMSD 1.24 Å
- 2M3D chain A against the predicted model Q9NR30: TM-score 0.82, RMSD 2.12 Å
- 2M3D chain A against the predicted model Q9NR30: TM-score 0.82, RMSD 2.12 Å
- 6L5O chain A against the predicted model Q9NR30: TM-score 0.64, RMSD 3.45 Å
- 6L5O chain A against the predicted model Q9NR30: TM-score 0.64, RMSD 3.45 Å
- 6L5L chain A against the predicted model Q9NR30: TM-score 0.60, RMSD 2.79 Å
- 6L5M chain E against the predicted model Q9NR30: TM-score 0.58, RMSD 1.97 Å
- 6L5M chain B against the predicted model Q9NR30: TM-score 0.58, RMSD 1.79 Å
- 6L5M chain C against the predicted model Q9NR30: TM-score 0.57, RMSD 1.59 Å
Elsewhere
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