UniProt Q9NQS5
G-protein coupled receptor 84 (Q9NQS5)
G-protein coupled receptor 84 (UniProt Q9NQS5): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NQS5
- Protein
- G-protein coupled receptor 84
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 17 · 3 records with a druggable one
Structures
5 records of Q9NQS5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8G05 | Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | electron microscopy | R | YI9, CLR | — |
| 8J18 | Cryo-EM structure of the 3-OH-C12-bound GPR84 receptor-Gi complex | electron microscopy | R | HXD | 7 (best 0.78) |
| 8J19 | Cryo-EM structure of the LY237-bound GPR84 receptor-Gi complex | electron microscopy | R | SWO | 4 (best 0.78) |
| 8J1A | Cryo-EM structure of the GPR84 receptor-Gi complex with no ligand modeled | electron microscopy | R | — | 6 (best 0.81) |
| Q9NQS5 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor 84 (Q9NQS5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8J19 chain R against the predicted model Q9NQS5: TM-score 0.92, RMSD 2.22 Å
- 8G05 chain R against the predicted model Q9NQS5: TM-score 0.91, RMSD 2.33 Å
- 8J18 chain R against the predicted model Q9NQS5: TM-score 0.91, RMSD 2.39 Å
- 8J1A chain R against the predicted model Q9NQS5: TM-score 0.90, RMSD 2.39 Å
Elsewhere
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