UniProt Q9NQB0
Transcription factor 7-like 2 (Q9NQB0)
Transcription factor 7-like 2 (UniProt Q9NQB0): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NQB0
- Protein
- Transcription factor 7-like 2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
7 records of Q9NQB0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JDH | Crystal structure of beta-catenin and htcf-4 | x-ray diffraction | B | — | — |
| 1JDH | Crystal structure of beta-catenin and htcf-4 | x-ray diffraction | B | — | — |
| 1JPW | Crystal Structure of a Human Tcf-4 / beta-Catenin Complex | x-ray diffraction | D, E, F | — | — |
| 1JPW | Crystal structure of a human tcf-4 / beta-catenin complex | x-ray diffraction | D, E, F | — | — |
| 2GL7 | Crystal Structure of a beta-catenin/BCL9/Tcf4 complex | x-ray diffraction | B, E | — | — |
| 2GL7 | Crystal structure of a beta-CATENIN/BCL9/TCF4 complex | x-ray diffraction | B, E | — | — |
| Q9NQB0 | AlphaFold monomer V2.0 prediction for transcription factor 7-like 2 (Q9NQB0) | predicted | A | — | 2 (best 0.45) |
Experiment against prediction
- 1JPW chain D against the predicted model Q9NQB0: TM-score 0.36, RMSD 1.76 Å
- 1JPW chain D against the predicted model Q9NQB0: TM-score 0.36, RMSD 1.76 Å
- 2GL7 chain B against the predicted model Q9NQB0: TM-score 0.35, RMSD 1.34 Å
- 2GL7 chain B against the predicted model Q9NQB0: TM-score 0.35, RMSD 1.34 Å
- 1JDH chain B against the predicted model Q9NQB0: TM-score 0.35, RMSD 3.19 Å
- 1JDH chain B against the predicted model Q9NQB0: TM-score 0.35, RMSD 3.19 Å
- 2GL7 chain E against the predicted model Q9NQB0: TM-score 0.29, RMSD 2.52 Å
- 2GL7 chain E against the predicted model Q9NQB0: TM-score 0.29, RMSD 2.52 Å
Elsewhere
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