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UniProt Q9NDD3

Thymidylate synthase (Q9NDD3)

Thymidylate synthase (UniProt Q9NDD3), EC 2.1.1.45: 4 experimental structures on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9NDD3
Protein
Thymidylate synthase
EC
2.1.1.45
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
17 · 2 records with a druggable one

Structures

4 records of Q9NDD3 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5BY6Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMPx-ray diffractionA, B, C, DUMP11 (best 0.77)
5BY6Crystal structure of trichinella spiralis thymidylate synthase complexed with dumpx-ray diffractionA, B, C, D——
5M4ZCrystal structure of the complex of T.spiralis thymidylate synthase with…x-ray diffractionA, B7K86 (best 0.65)
5M4ZCrystal structure of the complex of T.SPIRALIS thymidylate synthase with…x-ray diffractionA, B7K8—

Ligands

  • 7K8 · [(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate · in 2 records
  • UMP · 2'-deoxyuridine 5'-monophosphate · in 1 record

Elsewhere

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