UniProt Q9LKW9

Sodium/hydrogen exchanger 7 (Q9LKW9)

Sodium/hydrogen exchanger 7 (UniProt Q9LKW9): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 84 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9LKW9
Protein: Sodium/hydrogen exchanger 7
Experimental structures: 4
Predicted models: 1
Ligands: 2
Pockets: 84 · 5 records with a druggable one

Structures

5 records of Q9LKW9 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7Y3E	Cryo-EM structure of Arabidopsis thaliana SOS1 in an occluded state	electron microscopy	A, B	R16	18 (best 0.85)
8HYA	Cryo-EM structure of Arabidopsis thaliana SOS1 in an occluded state, with expanded TMD	electron microscopy	A, B	R16	20 (best 0.83)
8JD9	Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class1	electron microscopy	A, B	PC1	20 (best 0.85)
8JDA	Cyro-EM structure of the Na+/H+ antipoter SOS1 from Arabidopsis thaliana,class2	electron microscopy	A, B	—	11 (best 0.85)
Q9LKW9	AlphaFold monomer V2.0 prediction for SODIUM/HYDROGEN exchanger 7 (Q9LKW9)	predicted	A	—	15 (best 0.75)

Ligands

R16 · Hexadecane · in 2 records
PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 1 record

Experiment against prediction

8JDA chain B against the predicted model Q9LKW9: TM-score 0.95, RMSD 1.74 Å
8JDA chain A against the predicted model Q9LKW9: TM-score 0.95, RMSD 1.76 Å
8JD9 chain B against the predicted model Q9LKW9: TM-score 0.73, RMSD 5.99 Å
8JD9 chain A against the predicted model Q9LKW9: TM-score 0.73, RMSD 5.96 Å
7Y3E chain A against the predicted model Q9LKW9: TM-score 0.73, RMSD 6.02 Å
7Y3E chain B against the predicted model Q9LKW9: TM-score 0.73, RMSD 6.02 Å
8HYA chain B against the predicted model Q9LKW9: TM-score 0.72, RMSD 6.21 Å
8HYA chain A against the predicted model Q9LKW9: TM-score 0.72, RMSD 6.21 Å

Elsewhere

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