UniProt Q9JZQ3
5,10-methylenetetrahydrofolate reductase (Q9JZQ3)
5,10-methylenetetrahydrofolate reductase (UniProt Q9JZQ3), EC 1.5.1.20: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9JZQ3
- Protein
- 5,10-methylenetetrahydrofolate reductase
- EC
- 1.5.1.20
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
2 records of Q9JZQ3 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7RML | Neisseria meningitidis Methylenetetrahydrofolate reductase in complex with FAD | x-ray diffraction | A, B, C | FAD | 8 (best 0.72) |
| Q9JZQ3 | AlphaFold monomer V2.0 prediction for 5,10-methylenetetrahydrofolate reductase (Q9JZQ3) | predicted | A | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 1 record
Experiment against prediction
- 7RML chain B against the predicted model Q9JZQ3: TM-score 0.99, RMSD 0.70 Å
- 7RML chain A against the predicted model Q9JZQ3: TM-score 0.98, RMSD 0.61 Å
- 7RML chain C against the predicted model Q9JZQ3: TM-score 0.98, RMSD 0.82 Å
Elsewhere
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