UniProt Q9HCN6
Platelet glycoprotein VI (Q9HCN6)
Platelet glycoprotein VI (UniProt Q9HCN6): 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HCN6
- Protein
- Platelet glycoprotein VI
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 11 · 2 records with a druggable one
Structures
9 records of Q9HCN6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5OU7 | Crystal structure of the Glycoprotein VI loop truncation mutant PAVS-PAPYKN | x-ray diffraction | A, B, C, D | CL, PO4, NAG | 1 (best 0.28) |
| 5OU7 | Crystal structure of the glycoprotein VI loop truncation mutant pavs- papykn | x-ray diffraction | A, B, C, D | CL, PO4, NAG | — |
| 5OU8 | Crystal structure of Glycoprotein VI in complex with collagen-peptide (GPO)5 | x-ray diffraction | A, B | CL, NAG | — |
| 5OU8 | Crystal structure of glycoprotein VI in complex with collagen-peptide (GPO)5 | x-ray diffraction | A, B | CL, NAG | — |
| 5OU9 | Crystal structure of Glycoprotein VI in complex with collagen-peptide (GPO)3 | x-ray diffraction | A, B | NAG, CL | 2 (best 0.27) |
| 5OU9 | Crystal structure of glycoprotein VI in complex with collagen-peptide (GPO)3 | x-ray diffraction | A, B | NAG, CL | — |
| 7NMU | Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody. | x-ray diffraction | AAA, BBB | — | 5 (best 0.73) |
| 7R58 | Crystal structure of the GPVI-glenzocimab complex | x-ray diffraction | A | CL, SCN | 3 (best 0.62) |
| Q9HCN6 | AlphaFold monomer V2.0 prediction for platelet glycoprotein VI (Q9HCN6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7R58 chain A against the predicted model Q9HCN6: TM-score 0.97, RMSD 1.05 Å
- 5OU8 chain A against the predicted model Q9HCN6: TM-score 0.92, RMSD 1.97 Å
- 5OU8 chain A against the predicted model Q9HCN6: TM-score 0.92, RMSD 1.97 Å
- 5OU8 chain B against the predicted model Q9HCN6: TM-score 0.91, RMSD 1.75 Å
- 5OU8 chain B against the predicted model Q9HCN6: TM-score 0.91, RMSD 1.75 Å
- 5OU9 chain B against the predicted model Q9HCN6: TM-score 0.91, RMSD 1.80 Å
- 5OU9 chain B against the predicted model Q9HCN6: TM-score 0.91, RMSD 1.80 Å
- 5OU9 chain A against the predicted model Q9HCN6: TM-score 0.90, RMSD 2.16 Å
- 5OU9 chain A against the predicted model Q9HCN6: TM-score 0.90, RMSD 2.16 Å
- 5OU7 chain B against the predicted model Q9HCN6: TM-score 0.88, RMSD 2.23 Å
Elsewhere
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