UniProt Q9HBD1
Roquin-2 (Q9HBD1)
Roquin-2 (UniProt Q9HBD1): 7 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HBD1
- Protein
- Roquin-2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
8 records of Q9HBD1 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4Z30 | Crystal structure of the ROQ domain of human Roquin-2 | x-ray diffraction | A | — | — |
| 4Z30 | Crystal structure of the roq domain of human roquin-2 | x-ray diffraction | A | — | — |
| 4Z31 | Crystal structure of the RC3H2 ROQ domain in complex with stem-loop and double-stranded forms of RNA | x-ray diffraction | A, B | — | — |
| 4Z31 | Crystal structure of the RC3H2 roq domain in complex with stem-loop and double-stranded forms of RNA | x-ray diffraction | A, B | — | — |
| 4ZLC | Crystal structure of the roq domain of human roquin-2 | x-ray diffraction | A, B, C, D | — | — |
| 4ZLD | Crystal structure of human Roquin-2 ROQ domain in complex with Roquin CDE RNA | x-ray diffraction | A | — | 1 (best 0.64) |
| 4ZLD | Crystal structure of human roquin-2 roq domain in complex with roquin cde RNA | x-ray diffraction | A | — | — |
| Q9HBD1 | AlphaFold monomer V2.0 prediction for roquin-2 (Q9HBD1) | predicted | A | — | 4 (best 0.74) |
Experiment against prediction
- 4ZLC chain C against the predicted model Q9HBD1: TM-score 0.99, RMSD 0.55 Å
- 4ZLD chain A against the predicted model Q9HBD1: TM-score 0.98, RMSD 0.67 Å
- 4ZLD chain A against the predicted model Q9HBD1: TM-score 0.98, RMSD 0.67 Å
- 4Z31 chain B against the predicted model Q9HBD1: TM-score 0.98, RMSD 1.11 Å
- 4Z31 chain B against the predicted model Q9HBD1: TM-score 0.98, RMSD 1.11 Å
- 4ZLC chain D against the predicted model Q9HBD1: TM-score 0.97, RMSD 0.92 Å
- 4ZLC chain B against the predicted model Q9HBD1: TM-score 0.97, RMSD 1.23 Å
- 4Z31 chain A against the predicted model Q9HBD1: TM-score 0.97, RMSD 1.14 Å
- 4Z31 chain A against the predicted model Q9HBD1: TM-score 0.97, RMSD 1.14 Å
- 4ZLC chain A against the predicted model Q9HBD1: TM-score 0.97, RMSD 1.25 Å
Elsewhere
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