UniProt Q9H790
Exonuclease V (Q9H790)
Exonuclease V (UniProt Q9H790), EC 3.1.-.-: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H790
- Protein
- Exonuclease V
- EC
- 3.1.-.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 22 · 3 records with a druggable one
Structures
9 records of Q9H790 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7LW7 | Human Exonuclease 5 crystal structure | x-ray diffraction | A | SF4 | 6 (best 0.57) |
| 7LW7 | Human exonuclease 5 crystal structure | x-ray diffraction | A | SF4 | — |
| 7LW8 | Human Exonuclease 5 crystal structure in complex with a ssDNA | x-ray diffraction | A | SF4 | 5 (best 0.62) |
| 7LW8 | Human exonuclease 5 crystal structure in complex with a ssdna | x-ray diffraction | A | SF4 | — |
| 7LW9 | Human Exonuclease 5 crystal structure in complex with ssDNA, Sm, and Na | x-ray diffraction | A | SF4, SM, NA | 6 (best 0.68) |
| 7LW9 | Human exonuclease 5 crystal structure in complex with ssdna, sm, and na | x-ray diffraction | A | SF4, SM, NA | — |
| 7LWA | Human Exonuclease 5 crystal structure (T88E) in complex with ssDNA and Mg | x-ray diffraction | A | SF4, MG | 5 (best 0.49) |
| 7LWA | Human exonuclease 5 crystal structure (T88E) in complex with ssdna and mg | x-ray diffraction | A | SF4, MG | — |
| Q9H790 | AlphaFold monomer V2.0 prediction for exonuclease V (Q9H790) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7LW9 chain A against the predicted model Q9H790: TM-score 0.98, RMSD 0.95 Å
- 7LW9 chain A against the predicted model Q9H790: TM-score 0.98, RMSD 0.95 Å
- 7LW8 chain A against the predicted model Q9H790: TM-score 0.97, RMSD 1.01 Å
- 7LW8 chain A against the predicted model Q9H790: TM-score 0.97, RMSD 1.01 Å
- 7LWA chain A against the predicted model Q9H790: TM-score 0.97, RMSD 1.22 Å
- 7LWA chain A against the predicted model Q9H790: TM-score 0.97, RMSD 1.22 Å
- 7LW7 chain A against the predicted model Q9H790: TM-score 0.94, RMSD 1.69 Å
- 7LW7 chain A against the predicted model Q9H790: TM-score 0.94, RMSD 1.69 Å
Elsewhere
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