UniProt Q9H488
GDP-fucose protein O-fucosyltransferase 1 (Q9H488)
GDP-fucose protein O-fucosyltransferase 1 (UniProt Q9H488), EC 2.4.1.221: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9H488
- Protein
- GDP-fucose protein O-fucosyltransferase 1
- EC
- 2.4.1.221
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 3 records with a druggable one
Structures
5 records of Q9H488 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UX6 | Structure of Human POFUT1 in its apo form | x-ray diffraction | A, B | NAG | 5 (best 0.80) |
| 5UX6 | Structure of human POFUT1 in its apo form | x-ray diffraction | A, B | NAG | — |
| 5UXH | Structure of Human POFUT1 in complex with GDP-fucose | x-ray diffraction | A, B | GFB, NAG | 5 (best 0.81) |
| 5UXH | Structure of human POFUT1 in complex with GDP-fucose | x-ray diffraction | A, B | GFB, NAG | — |
| Q9H488 | AlphaFold monomer V2.0 prediction for GDP-fucose protein O-fucosyltransferase 1 (Q9H488) | predicted | A | — | 4 (best 0.66) |
Ligands
Experiment against prediction
- 5UXH chain A against the predicted model Q9H488: TM-score 0.99, RMSD 0.50 Å
- 5UXH chain A against the predicted model Q9H488: TM-score 0.99, RMSD 0.50 Å
- 5UX6 chain A against the predicted model Q9H488: TM-score 0.99, RMSD 0.52 Å
- 5UX6 chain A against the predicted model Q9H488: TM-score 0.99, RMSD 0.52 Å
- 5UXH chain B against the predicted model Q9H488: TM-score 0.99, RMSD 0.69 Å
- 5UXH chain B against the predicted model Q9H488: TM-score 0.99, RMSD 0.69 Å
- 5UX6 chain B against the predicted model Q9H488: TM-score 0.97, RMSD 1.43 Å
- 5UX6 chain B against the predicted model Q9H488: TM-score 0.97, RMSD 1.43 Å
Elsewhere
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