UniProt Q9H3M7
Thioredoxin-interacting protein (Q9H3M7)
Thioredoxin-interacting protein (UniProt Q9H3M7): 18 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H3M7
- Protein
- Thioredoxin-interacting protein
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
19 records of Q9H3M7 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GEI | N-terminal domain of VDUP-1 | x-ray diffraction | A | — | — |
| 4GEI | N-terminal domain of vdup-1 | x-ray diffraction | A | — | — |
| 4GEJ | N-terminal domain of VDUP-1 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4GEJ | N-terminal domain of vdup-1 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 4GFX | Crystal structure of the N-terminal domain of TXNIP | x-ray diffraction | A | — | — |
| 4GFX | Crystal structure of the N-terminal domain of txnip | x-ray diffraction | A | — | — |
| 4LL1 | The structure of the TRX and TXNIP complex | x-ray diffraction | A, C | — | — |
| 4LL1 | The structure of the trx and txnip complex | x-ray diffraction | A, C | — | — |
| 4LL4 | The structure of the TRX and TXNIP complex | x-ray diffraction | A, C | — | — |
| 4LL4 | The structure of the trx and txnip complex | x-ray diffraction | A, C | — | — |
| 4ROF | Crystal Structure of WW3 domain of ITCH in complex with TXNIP peptide | x-ray diffraction | C, D | — | — |
| 4ROF | Crystal structure of WW3 domain of itch in complex with txnip peptide | x-ray diffraction | C, D | — | — |
| 4ROJ | Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide | x-ray diffraction | D, E, F | — | — |
| 4ROJ | Crystal structure of the VAV2 SH2 domain in complex with txnip phosphorylated peptide | x-ray diffraction | D, E, F | — | — |
| 5CQ2 | Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide | x-ray diffraction | B, C | UNX | — |
| 5CQ2 | Crystal structure of tandem ww domains of itch in complex with txnip peptide | x-ray diffraction | B, C | — | — |
| 5DZD | Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide | x-ray diffraction | C, D | UNX | — |
| 5DZD | Crystal structure of WW4 domain of itch in complex with txnip peptide | x-ray diffraction | C, D | — | — |
| Q9H3M7 | AlphaFold monomer V2.0 prediction for thioredoxin-interacting protein (Q9H3M7) | predicted | A | — | 1 (best 0.34) |
Ligands
- UNX · Unknown atom or ion · in 2 records
Experiment against prediction
- 4GEJ chain A against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.80 Å
- 4GEJ chain A against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.80 Å
- 4GEJ chain B against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.77 Å
- 4GEJ chain B against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.77 Å
- 4GEJ chain E against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.88 Å
- 4GEJ chain E against the predicted model Q9H3M7: TM-score 0.92, RMSD 1.88 Å
- 4GEJ chain J against the predicted model Q9H3M7: TM-score 0.91, RMSD 1.80 Å
- 4GEJ chain J against the predicted model Q9H3M7: TM-score 0.91, RMSD 1.80 Å
- 4GEJ chain D against the predicted model Q9H3M7: TM-score 0.91, RMSD 1.78 Å
- 4GEJ chain D against the predicted model Q9H3M7: TM-score 0.91, RMSD 1.78 Å
Elsewhere
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