UniProt Q9H2F5
Enhancer of polycomb homolog 1 (Q9H2F5)
Enhancer of polycomb homolog 1 (UniProt Q9H2F5): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H2F5
- Protein
- Enhancer of polycomb homolog 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 7 records with a druggable one
Structures
9 records of Q9H2F5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NFX | MBTD1 MBT repeats | x-ray diffraction | A | UNX, NA | 5 (best 0.80) |
| 6NFX | MBTD1 mbt repeats | x-ray diffraction | A | UNX, NA | — |
| 8QR1 | Cryo-EM structure of the human Tip60 complex | electron microscopy | C | — | 2 (best 0.79) |
| 8XVG | Structure of human NuA4/TIP60 complex | electron microscopy | M | — | 1 (best 0.82) |
| 8XVT | The core subcomplex of human NuA4/TIP60 complex | electron microscopy | M | — | 3 (best 0.83) |
| 9C57 | Reconstituted P400 Subcomplex of the human TIP60 complex | electron microscopy | H | — | 1 (best 0.83) |
| 9C62 | P400 subcomplex of the native human TIP60 complex | electron microscopy | H | — | 1 (best 0.88) |
| 9C6N | ARP module of the human TIP60 complex | electron microscopy | H | — | 9 (best 0.81) |
| Q9H2F5 | AlphaFold monomer V2.0 prediction for enhancer of polycomb homolog 1 (Q9H2F5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6NFX chain A against the predicted model Q05BQ5: TM-score 0.95, RMSD 0.87 Å
- 6NFX chain A against the predicted model Q05BQ5: TM-score 0.95, RMSD 0.87 Å
- 9C57 chain H against the predicted model Q9H2F5: TM-score 0.79, RMSD 1.76 Å
- 9C6N chain H against the predicted model Q9H2F5: TM-score 0.77, RMSD 1.96 Å
- 9C62 chain H against the predicted model Q9H2F5: TM-score 0.60, RMSD 2.73 Å
- 8QR1 chain C against the predicted model Q9H2F5: TM-score 0.58, RMSD 2.36 Å
- 8XVG chain M against the predicted model Q9H2F5: TM-score 0.50, RMSD 3.40 Å
- 8XVT chain M against the predicted model Q9H2F5: TM-score 0.50, RMSD 3.40 Å
- 6NFX chain A against the predicted model Q9H2F5: TM-score 0.22, RMSD 7.36 Å
- 6NFX chain A against the predicted model Q9H2F5: TM-score 0.22, RMSD 7.36 Å
Elsewhere
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