UniProt Q9H293
Interleukin-25 (Q9H293)
Interleukin-25 (UniProt Q9H293): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H293
- Protein
- Interleukin-25
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 27 · 2 records with a druggable one
Structures
6 records of Q9H293 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UWJ | Structure of the homodimeric IL-25-IL-17RB binary complex | electron microscopy | A, B | NAG | 10 (best 0.78) |
| 7UWJ | Structure of the homodimeric il-25-il-17RB binary complex | electron microscopy | A, B | NAG | — |
| 7UWK | Structure of the higher-order IL-25-IL-17RB complex | electron microscopy | A, B, E, G, F, H | — | 17 (best 0.86) |
| 7UWK | Structure of the higher-order il-25-il-17RB complex | electron microscopy | A, B, E, G, F, H | — | — |
| 7UWL | Structure of the il-25-il-17RB-il-17RA ternary complex | electron microscopy | A, B | NAG | — |
| Q9H293 | AlphaFold monomer V2.0 prediction for interleukin-25 (Q9H293) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
Experiment against prediction
- 7UWL chain B against the predicted model Q9H293: TM-score 0.88, RMSD 1.47 Å
- 7UWL chain A against the predicted model Q9H293: TM-score 0.88, RMSD 1.47 Å
- 7UWJ chain A against the predicted model Q9H293: TM-score 0.88, RMSD 1.50 Å
- 7UWJ chain A against the predicted model Q9H293: TM-score 0.88, RMSD 1.50 Å
- 7UWJ chain B against the predicted model Q9H293: TM-score 0.88, RMSD 1.53 Å
- 7UWJ chain B against the predicted model Q9H293: TM-score 0.88, RMSD 1.53 Å
- 7UWK chain G against the predicted model Q9H293: TM-score 0.86, RMSD 1.66 Å
- 7UWK chain G against the predicted model Q9H293: TM-score 0.86, RMSD 1.66 Å
- 7UWK chain A against the predicted model Q9H293: TM-score 0.86, RMSD 1.68 Å
- 7UWK chain A against the predicted model Q9H293: TM-score 0.86, RMSD 1.68 Å
Elsewhere
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