UniProt Q9H0F5
E3 ubiquitin-protein ligase RNF38 (Q9H0F5)
E3 ubiquitin-protein ligase RNF38 (UniProt Q9H0F5), EC 2.3.2.27, 6.3.2.19: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9H0F5
- Protein
- E3 ubiquitin-protein ligase RNF38
- EC
- 2.3.2.27, 6.3.2.19
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
9 records of Q9H0F5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1X4J | Solution structure of RING finger in RING finger protein 38 | solution nmr | A | ZN | 1 (best 0.42) |
| 1X4J | Solution structure of ring finger in ring finger protein 38 | solution nmr | A | — | — |
| 4V3K | RNF38-UbcH5B-UB complex | x-ray diffraction | C, F | — | — |
| 4V3K | RNF38-UBCH5B-ub complex | x-ray diffraction | C, F | — | — |
| 4V3L | RNF38-UB-UbcH5B-Ub complex | x-ray diffraction | C | ZN | 3 (best 0.54) |
| 4V3L | RNF38-ub-UBCH5B-ub complex | x-ray diffraction | C | — | — |
| 7OJX | E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain… | x-ray diffraction | A | ZN | 3 (best 0.60) |
| 7OJX | E2 UBE2K covalently linked to donor ub, acceptor di-ub, and ring E3 primed for K48-linked ub chain… | x-ray diffraction | A | ZN | — |
| Q9H0F5 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF38 (Q9H0F5) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 4V3L chain C against the predicted model Q9H0F5: TM-score 0.98, RMSD 0.51 Å
- 4V3L chain C against the predicted model Q9H0F5: TM-score 0.98, RMSD 0.51 Å
- 4V3K chain F against the predicted model Q9H0F5: TM-score 0.97, RMSD 0.74 Å
- 4V3K chain F against the predicted model Q9H0F5: TM-score 0.97, RMSD 0.74 Å
- 7OJX chain A against the predicted model Q9H0F5: TM-score 0.96, RMSD 0.67 Å
- 7OJX chain A against the predicted model Q9H0F5: TM-score 0.96, RMSD 0.67 Å
- 4V3K chain C against the predicted model Q9H0F5: TM-score 0.95, RMSD 0.93 Å
- 4V3K chain C against the predicted model Q9H0F5: TM-score 0.95, RMSD 0.93 Å
- 1X4J chain A against the predicted model Q9H0F5: TM-score 0.77, RMSD 1.45 Å
- 1X4J chain A against the predicted model Q9H0F5: TM-score 0.77, RMSD 1.45 Å
Elsewhere
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