UniProt Q9CZW6
E3 ubiquitin-protein ligase RNF146 (Q9CZW6)
E3 ubiquitin-protein ligase RNF146 (UniProt Q9CZW6): 6 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9CZW6
- Protein
- E3 ubiquitin-protein ligase RNF146
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
7 records of Q9CZW6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1UJR | Solution structure of WWE domain in BAB28015 | solution nmr | A | — | — |
| 1UJR | Solution structure of wwe domain in BAB28015 | solution nmr | A | — | — |
| 2RSF | Complex structure of WWE in RNF146 with ATP | solution nmr | A | — | — |
| 2RSF | Complex structure of wwe in RNF146 with ATP | solution nmr | A | — | — |
| 4QPL | Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex | x-ray diffraction | A, C | — | — |
| 4QPL | Crystal structure of RNF146(RING-WWE)/UBCH5A/ISO-adpr complex | x-ray diffraction | A, C | — | — |
| Q9CZW6 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF146 (Q9CZW6) | predicted | A | — | 5 (best 0.62) |
Experiment against prediction
- 4QPL chain A against the predicted model Q9CZW6: TM-score 0.97, RMSD 1.04 Å
- 4QPL chain A against the predicted model Q9CZW6: TM-score 0.97, RMSD 1.04 Å
- 1UJR chain A against the predicted model Q9CZW6: TM-score 0.59, RMSD 2.00 Å
- 1UJR chain A against the predicted model Q9CZW6: TM-score 0.59, RMSD 2.00 Å
- 2RSF chain A against the predicted model Q9CZW6: TM-score 0.58, RMSD 2.23 Å
- 2RSF chain A against the predicted model Q9CZW6: TM-score 0.58, RMSD 2.23 Å
Elsewhere
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