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Ligand · V3L

V3L · 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate)

V3L, 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate) (C15 H23 N5 O14 P2, 559.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5…

Component
V3L
Formula
C15 H23 N5 O14 P2
Class
ligand
Structures
8
PDB entries
4

Binding sites

V3L in 8 structures; the first of them:

  • 3V3L · Crystal structure of human RNF146 WWE domain in complex with iso-ADPRibose · V3L A1 · binds TYR107, GLY109, ARG110, ASN111, TRP114, TYR116, ILE139, TYR144 and 11 more
  • 4N9Y · Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain mutant… · V3L A1007 · binds PRO469, VAL475, VAL477, ARG478, VAL479, ASP480, PHE491, THR493
  • 4N9Z · Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain mutant… · V3L A1001 · binds PRO469, VAL475, VAL477, ARG478, VAL479, ASP480, PHE491, THR493
  • 4QPL · Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex · V3L A201 · binds LEU58, LYS61, TRP65, TYR107, GLY109, ARG110, TRP114, TYR116 and 9 more
  • 3V3L · Crystal structure of human RNF146 wwe domain in complex with iso- adpribose · V3L A1 · binds TYR107, GLY109, ARG110, ASN111, TRP114, TYR116, ILE139, TYR144 and 11 more
  • 4N9Y · Crystal structure of mouse POLY(ADP-ribose) glycohydrolase (parg) catalytic domain mutant… · V3L A1007 · binds PRO469, VAL475, VAL477, ARG478, VAL479, ASP480, PHE491, THR493
  • 4N9Z · Crystal structure of mouse POLY(ADP-ribose) glycohydrolase (parg) catalytic domain mutant… · V3L A1001 · binds PRO469, VAL475, VAL477, ARG478, VAL479, ASP480, PHE491, THR493
  • 4QPL · Crystal structure of RNF146(RING-WWE)/UBCH5A/ISO-adpr complex · V3L A201 · binds LEU58, LYS61, TRP65, TYR107, GLY109, ARG110, TRP114, TYR116 and 9 more

Residues it binds most

ARG 14, TYR 8, GLY 8, VAL 6, LYS 8, TRP 8, ALA 8, GLN 8, ILE 8, ASP 6 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • ZN · Zinc ion

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