UniProt Q9BVA6
Protein adenylyltransferase FICD (Q9BVA6)
Protein adenylyltransferase FICD (UniProt Q9BVA6), EC 2.7.7.-, 3.1.4.-: 26 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9BVA6
- Protein
- Protein adenylyltransferase FICD
- EC
- 2.7.7.-, 3.1.4.-
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 23 · 3 records with a druggable one
Structures
27 records of Q9BVA6 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4U04 | Structure of a eukaryotic fic domain containing protein | x-ray diffraction | A, B | — | — |
| 4U04 | Structure of a eukaryotic fic domain containing protein | x-ray diffraction | A, B | — | — |
| 4U07 | ATP bound to eukaryotic FIC domain containing protein | x-ray diffraction | A, B | — | — |
| 4U07 | ATP bound to eukaryotic fic domain containing protein | x-ray diffraction | A, B | — | — |
| 4U0S | Structure of Eukaryotic fic domain containing protein with ADP | x-ray diffraction | A, B | — | — |
| 4U0S | Structure of eukaryotic fic domain containing protein with ADP | x-ray diffraction | A, B | — | — |
| 4U0U | Wild type eukaryotic fic domain containing protein with ADP | x-ray diffraction | A, B | — | — |
| 4U0U | Wild type eukaryotic fic domain containing protein with ADP | x-ray diffraction | A, B | — | — |
| 4U0Z | Eukaryotic Fic Domain containing protein with bound APCPP | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4U0Z | Eukaryotic fic domain containing protein with bound apcpp | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 6I7G | Crystal structure of dimeric wild type ficd complexed with ATP | x-ray diffraction | A, B | ATP | — |
| 6I7H | Crystal structure of dimeric FICD mutant K256S | x-ray diffraction | A | MG | — |
| 6I7H | Crystal structure of dimeric ficd mutant K256S | x-ray diffraction | A | MG | — |
| 6I7I | Crystal structure of dimeric FICD mutant K256A complexed with MgATP | x-ray diffraction | A | MG, ATP | — |
| 6I7I | Crystal structure of dimeric ficd mutant K256A complexed with mgatp | x-ray diffraction | A | MG, ATP | — |
| 6I7J | Crystal structure of monomeric ficd mutant L258D | x-ray diffraction | A | SO4 | — |
| 6I7K | Crystal structure of monomeric FICD mutant L258D complexed with MgATP | x-ray diffraction | A | MG, ATP | — |
| 6I7K | Crystal structure of monomeric ficd mutant L258D complexed with mgatp | x-ray diffraction | A | MG, ATP | — |
| 6I7L | Crystal structure of monomeric FICD mutant L258D complexed with MgAMP-PNP | x-ray diffraction | A | ANP, MG | — |
| 6I7L | Crystal structure of monomeric ficd mutant L258D complexed with mgamp- pnp | x-ray diffraction | A | ANP, MG | — |
| 6ZMD | Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | x-ray diffraction | B | QMK, PO4 | 8 (best 0.75) |
| 6ZMD | Crystal structure of hype covalently tethered to bip bound to AMP-pnp | x-ray diffraction | B | QMK, PO4 | — |
| 7B7Z | DeAMPylation complex of monomeric FICD and AMPylated BiP (state 1) | x-ray diffraction | A | AMP, MG | 6 (best 0.77) |
| 7B7Z | Deampylation complex of monomeric ficd and ampylated bip (state 1) | x-ray diffraction | A | AMP, MG | — |
| 7B80 | DeAMPylation complex of monomeric FICD and AMPylated BiP (state 2) | x-ray diffraction | A | AMP, MG | 9 (best 0.75) |
| 7B80 | Deampylation complex of monomeric ficd and ampylated bip (state 2) | x-ray diffraction | A | AMP, MG | — |
| Q9BVA6 | AlphaFold monomer V2.0 prediction for protein adenylyltransferase ficd (Q9BVA6) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 12 records
- ATP · Adenosine-5'-triphosphate · in 5 records
- AMP · Adenosine monophosphate · in 4 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- PO4 · Phosphate ion · in 2 records
- QMK · ~{N}-[2-[1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[[tris(oxidanyl)-$l^{5}-phosphanyl]oxymethyl]oxolan-2-yl]-1,2,3-triazol-4-yl]ethyl]ethanamide · in 2 records
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 6I7J chain A against the predicted model Q9BVA6: TM-score 0.99, RMSD 0.67 Å
- 6I7H chain A against the predicted model Q9BVA6: TM-score 0.99, RMSD 0.74 Å
- 6I7H chain A against the predicted model Q9BVA6: TM-score 0.99, RMSD 0.74 Å
- 4U04 chain B against the predicted model Q9BVA6: TM-score 0.99, RMSD 0.79 Å
- 4U04 chain B against the predicted model Q9BVA6: TM-score 0.99, RMSD 0.79 Å
- 4U07 chain B against the predicted model Q9BVA6: TM-score 0.98, RMSD 0.86 Å
- 4U07 chain B against the predicted model Q9BVA6: TM-score 0.98, RMSD 0.86 Å
- 4U0S chain B against the predicted model Q9BVA6: TM-score 0.98, RMSD 0.87 Å
- 4U0S chain B against the predicted model Q9BVA6: TM-score 0.98, RMSD 0.87 Å
- 4U0U chain B against the predicted model Q9BVA6: TM-score 0.98, RMSD 0.88 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.