UniProt Q9BUI4
DNA-directed RNA polymerase III subunit RPC3 (Q9BUI4)
DNA-directed RNA polymerase III subunit RPC3 (UniProt Q9BUI4): 23 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9BUI4
- Protein
- DNA-directed RNA polymerase III subunit RPC3
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 30 · 7 records with a druggable one
Structures
24 records of Q9BUI4 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XUB | Human RPC62 subunit structure | x-ray diffraction | A | — | — |
| 2XUB | Human RPC62 subunit structure | x-ray diffraction | A | — | — |
| 2XV4 | Structure of Human RPC62 (partial) | x-ray diffraction | S | — | — |
| 2XV4 | Structure of human RPC62 (partial) | x-ray diffraction | S | — | — |
| 5AFQ | Crystal structure of RPC62 - RPC32 beta | x-ray diffraction | A, B | — | — |
| 5AFQ | Crystal structure of RPC62 - RPC32 beta | x-ray diffraction | A, B | — | — |
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | O | — | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | O | SF4 | 5 (best 0.82) |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | O | SF4 | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | O | SF4 | 3 (best 0.85) |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | O | SF4 | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | O | SF4 | 5 (best 0.83) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | O | SF4 | — |
| 7AST | Apo human RNA polymerase III | electron microscopy | X | — | — |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | O | SF4 | — |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | O | SF4 | — |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | O | SF4 | — |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | O | SF4 | — |
| 7FJI | human Pol III elongation complex | electron microscopy | O | SF4 | 6 (best 0.80) |
| 7FJI | Human pol III elongation complex | electron microscopy | O | SF4 | — |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | O | SF4 | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | O | SF4 | 3 (best 0.86) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | O | SF4 | 3 (best 0.81) |
| Q9BUI4 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC3 (Q9BUI4) | predicted | A | — | 5 (best 0.59) |
Ligands
- SF4 · Iron/sulfur cluster · in 15 records
Experiment against prediction
- 8ITY chain O against the predicted model Q9BUI4: TM-score 0.96, RMSD 1.80 Å
- 7A6H chain O against the predicted model Q9BUI4: TM-score 0.96, RMSD 1.84 Å
- 8IUE chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 2.08 Å
- 7AE1 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 2.11 Å
- 7AE1 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 2.11 Å
- 7AE3 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 2.10 Å
- 7AE3 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 2.10 Å
- 7DU2 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 1.93 Å
- 7DN3 chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 1.93 Å
- 7FJJ chain O against the predicted model Q9BUI4: TM-score 0.95, RMSD 1.93 Å
Elsewhere
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