UniProt Q99P21
Adenine DNA glycosylase (Q99P21)
Adenine DNA glycosylase (UniProt Q99P21): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99P21
- Protein
- Adenine DNA glycosylase
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of Q99P21 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EF8 | Crystal structure of mouse mutyh in complex with DNA containing ap site ANALOGUE:8-oxog (form I) | x-ray diffraction | A | SF4, ZN, SO4 | — |
| 7EF9 | Crystal structure of mouse mutyh in complex with DNA containing ap site ANALOGUE:8-oxog (form II) | x-ray diffraction | A | SF4, ZN, SO4 | — |
| 7EFA | Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA | x-ray diffraction | B | — | — |
| 7EFA | Crystal structure of the complex between the C-terminal domain of mouse mutyh and human PCNA | x-ray diffraction | B | — | — |
| Q99P21 | AlphaFold monomer V2.0 prediction for adenine DNA glycosylase (Q99P21) | predicted | A | — | 7 (best 0.60) |
Ligands
Experiment against prediction
- 7EF8 chain A against the predicted model Q99P21: TM-score 0.98, RMSD 1.24 Å
- 7EF9 chain A against the predicted model Q99P21: TM-score 0.96, RMSD 1.65 Å
- 7EFA chain B against the predicted model Q99P21: TM-score 0.85, RMSD 1.36 Å
- 7EFA chain B against the predicted model Q99P21: TM-score 0.85, RMSD 1.36 Å
Elsewhere
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