UniProt Q99KQ4
Nicotinamide phosphoribosyltransferase (Q99KQ4)
Nicotinamide phosphoribosyltransferase (UniProt Q99KQ4): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99KQ4
- Protein
- Nicotinamide phosphoribosyltransferase
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 1 record with a druggable one
Structures
8 records of Q99KQ4 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GVL | Crystal Structure of Murine NMPRTase | x-ray diffraction | A, B | — | — |
| 2GVL | Crystal structure of murine nmprtase | x-ray diffraction | A, B | — | — |
| 2H3B | Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony… | x-ray diffraction | A, B | — | — |
| 2H3B | Crystal structure of mouse nicotinamide PHOSPHORIBOSYLTRANSFERASE/VISFATIN/PRE-B cell colony… | x-ray diffraction | A, B | — | — |
| 2H3D | Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony… | x-ray diffraction | A, B | — | — |
| 2H3D | Crystal structure of mouse nicotinamide PHOSPHORIBOSYLTRANSFERASE/VISFATIN/PRE-B cell colony… | x-ray diffraction | A, B | — | — |
| 7Q8T | Crystal structure of nampt bound to ligand TSY535(COMPOUND 9A) | x-ray diffraction | A, B | 9IY, SO4 | — |
| Q99KQ4 | AlphaFold monomer V2.0 prediction for nicotinamide phosphoribosyltransferase (Q99KQ4) | predicted | A | — | 6 (best 0.61) |
Ligands
Experiment against prediction
- 2H3D chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.43 Å
- 2H3D chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.43 Å
- 2H3D chain B against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.47 Å
- 2H3D chain B against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.47 Å
- 2H3B chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.52 Å
- 2H3B chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.52 Å
- 2GVL chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.55 Å
- 2GVL chain A against the predicted model Q99KQ4: TM-score 1.00, RMSD 0.55 Å
- 7Q8T chain A against the predicted model Q99KQ4: TM-score 0.99, RMSD 0.65 Å
Elsewhere
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