UniProt Q99967
Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha (Q99967)
Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha (UniProt Q99967): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q99967
- Protein
- Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of Q99967 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1P4Q | Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain | solution nmr | A | — | — |
| 1P4Q | Solution structure of the CITED2 transactivation domain in complex with the P300 CH1 domain | solution nmr | A | — | — |
| 1R8U | NMR structure of CBP TAZ1/CITED2 complex | solution nmr | A | — | — |
| 1R8U | NMR structure of cbp TAZ1/CITED2 complex | solution nmr | A | — | — |
| 7LVS | The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide | x-ray diffraction | F | — | 2 (best 0.54) |
| 7LVS | The cbp TAZ1 domain in complex with a CITED2-hif-1-alpha fusion peptide | x-ray diffraction | F | — | — |
| 7QGS | Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid) | x-ray diffraction | B | — | — |
| 7QGS | Crystal structure of P300 CH1 domain in complex with citif (a CITED2- hif-1ALPHA hybrid) | x-ray diffraction | B | — | — |
| Q99967 | AlphaFold monomer V2.0 prediction for CBP/P300-interacting transactivator 2 (Q99967) | predicted | A | — | — |
Experiment against prediction
- 1P4Q chain A against the predicted model Q99967: TM-score 0.59, RMSD 2.48 Å
- 1P4Q chain A against the predicted model Q99967: TM-score 0.59, RMSD 2.48 Å
- 1R8U chain A against the predicted model Q99967: TM-score 0.51, RMSD 2.32 Å
- 1R8U chain A against the predicted model Q99967: TM-score 0.51, RMSD 2.32 Å
- 7LVS chain F against the predicted model Q99967: TM-score 0.47, RMSD 3.17 Å
- 7LVS chain F against the predicted model Q99967: TM-score 0.47, RMSD 3.17 Å
- 7QGS chain B against the predicted model Q99967: TM-score 0.44, RMSD 2.18 Å
- 7QGS chain B against the predicted model Q99967: TM-score 0.44, RMSD 2.18 Å
- 7QGS chain B against the predicted model Q16665: TM-score 0.35, RMSD 3.35 Å
- 7QGS chain B against the predicted model Q16665: TM-score 0.35, RMSD 3.35 Å
Elsewhere
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