UniProt Q99933
Bag family molecular chaperone regulator 1 (Q99933)
Bag family molecular chaperone regulator 1 (UniProt Q99933): 47 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99933
- Protein
- Bag family molecular chaperone regulator 1
- Experimental structures
- 47
- Predicted models
- 1
- Pockets
- 22 · 3 records with a druggable one
Structures
48 records of Q99933 in the MolNFT archive: 47 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HX1 | Crystal structure of a bag domain in complex with the HSC70 ATPase domain | x-ray diffraction | B | — | — |
| 1HX1 | Crystal structure of a bag domain in complex with the HSC70 ATPase domain | x-ray diffraction | B | — | — |
| 1WXV | Solution structure of the ubiquitin domain of BCL-2 binding athanogene-1 | solution nmr | A | — | — |
| 1WXV | Solution structure of the ubiquitin domain of BCL-2 binding athanogene-1 | solution nmr | A | — | — |
| 3FZF | Crystal Structure of Hsc70/Bag1 in complex with ATP | x-ray diffraction | B | — | — |
| 3FZF | Crystal structure of HSC70/BAG1 in complex with ATP | x-ray diffraction | B | — | — |
| 3FZH | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | x-ray diffraction | B | — | — |
| 3FZH | Crystal structures of HSC70/BAG1 in complex with small molecule inhibitors | x-ray diffraction | B | — | — |
| 3FZK | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | x-ray diffraction | B | — | — |
| 3FZK | Crystal structures of HSC70/BAG1 in complex with small molecule inhibitors | x-ray diffraction | B | — | — |
| 3FZL | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | x-ray diffraction | B | — | — |
| 3FZL | Crystal structures of HSC70/BAG1 in complex with small molecule inhibitors | x-ray diffraction | B | — | — |
| 3FZM | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | x-ray diffraction | B | — | — |
| 3FZM | Crystal structures of HSC70/BAG1 in complex with small molecule inhibitors | x-ray diffraction | B | — | — |
| 3LDQ | Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor | x-ray diffraction | B | — | — |
| 3LDQ | Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor | x-ray diffraction | B | — | — |
| 3M3Z | Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor | x-ray diffraction | B | — | — |
| 3M3Z | Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor | x-ray diffraction | B | — | — |
| 5AQF | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQF | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQG | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | 8 (best 0.73) |
| 5AQG | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQH | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQH | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQI | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQI | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQJ | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQK | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQK | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQL | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQL | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQM | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQM | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQN | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQO | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQP | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | 12 (best 0.73) |
| 5AQP | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQQ | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQR | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D, F | — | — |
| 5AQS | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQS | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B, D | — | — |
| 5AQT | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQT | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQU | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQU | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| 5AQV | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | 2 (best 0.73) |
| 5AQV | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | x-ray diffraction | B | — | — |
| Q99933 | AlphaFold monomer V2.0 prediction for bag family molecular chaperone regulator 1 (Q99933) | predicted | A | — | — |
Experiment against prediction
- 5AQQ chain B against the predicted model Q99933: TM-score 0.97, RMSD 0.76 Å
- 3LDQ chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.82 Å
- 3LDQ chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.82 Å
- 5AQK chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.80 Å
- 5AQK chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.80 Å
- 3FZL chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.87 Å
- 3FZL chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.87 Å
- 3FZK chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.87 Å
- 3FZK chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.87 Å
- 3FZM chain B against the predicted model Q99933: TM-score 0.96, RMSD 0.86 Å
Elsewhere
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