UniProt Q99714
3-hydroxyacyl-CoA dehydrogenase type-2 (Q99714)
3-hydroxyacyl-CoA dehydrogenase type-2 (UniProt Q99714), EC 1.1.1.159, 1.1.1.178: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q99714
- Protein
- 3-hydroxyacyl-CoA dehydrogenase type-2
- EC
- 1.1.1.159, 1.1.1.178, 1.1.1.239, 1.1.1.35, 1.1.1.53, 1.1.1.62
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 2 records with a druggable one
Structures
9 records of Q99714 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SO8 | Abeta-bound human ABAD structure [also known as 3-hydroxyacyl-CoA dehydrogenase type II (Type II… | x-ray diffraction | A | — | — |
| 1SO8 | Abeta-bound human abad structure [also known as 3-hydroxyacyl-CoA dehydrogenase type II (type II… | x-ray diffraction | A | — | — |
| 1U7T | Crystal Structure of ABAD/HSD10 with a Bound Inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 1U7T | Crystal structure of ABAD/HSD10 with a bound inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 7ONU | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr | electron microscopy | A, B, C, D | NAD | 13 (best 0.85) |
| 7ONU | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-tyr | electron microscopy | A, B, C, D | NAD | — |
| 8CBL | Structure of human mitochondrial RNase Z in complex with mitochondrial pre-tRNA-His(0,Ser) | electron microscopy | A, B, C, D | NAD | 7 (best 0.86) |
| 8CBO | Structure of human mitochondrial MRPP1-MRPP2 in complex with mitochondrial pre-tRNA-Ile | electron microscopy | A, B, C, D | NAD | — |
| Q99714 | AlphaFold monomer V2.0 prediction for 3-hydroxyacyl-CoA dehydrogenase type-2 (Q99714) | predicted | A | — | — |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 4 records
Experiment against prediction
- 8CBO chain D against the predicted model Q99714: TM-score 0.99, RMSD 0.43 Å
- 8CBO chain C against the predicted model Q99714: TM-score 0.99, RMSD 0.44 Å
- 8CBL chain C against the predicted model Q99714: TM-score 0.99, RMSD 0.45 Å
- 8CBL chain B against the predicted model Q99714: TM-score 0.99, RMSD 0.50 Å
- 7ONU chain C against the predicted model Q99714: TM-score 0.99, RMSD 0.53 Å
- 7ONU chain C against the predicted model Q99714: TM-score 0.99, RMSD 0.53 Å
- 8CBL chain D against the predicted model Q99714: TM-score 0.99, RMSD 0.58 Å
- 7ONU chain D against the predicted model Q99714: TM-score 0.99, RMSD 0.64 Å
- 7ONU chain D against the predicted model Q99714: TM-score 0.99, RMSD 0.64 Å
- 1U7T chain A against the predicted model Q99714: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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