UniProt Q99603

T cell receptor gamma variable 9,T cell receptor gamma constant 1 (Q99603)

T cell receptor gamma variable 9,T cell receptor gamma constant 1 (UniProt Q99603): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against…

UniProt: Q99603
Protein: T cell receptor gamma variable 9,T cell receptor gamma constant 1
Experimental structures: 4
Predicted models: 1
Ligands: 1
Pockets: 18 · 4 records with a druggable one

Structures

5 records of Q99603 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8JC0	V gamma9 V delta2 TCR and CD3 complex in LMNG	electron microscopy	n	CLR	4 (best 0.82)
8WY0	T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A	electron microscopy	n	CLR	4 (best 0.82)
8WYI	T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC	electron microscopy	n	—	4 (best 0.82)
8YC0	T cell receptor V delta2 V gamma9 in GDN	electron microscopy	n	CLR	5 (best 0.81)
Q99603	AlphaFold monomer V2.0 prediction for T cell receptor gamma variable 9 (Q99603)	predicted	A	—	1 (best 0.44)

Ligands

CLR · Cholesterol · in 3 records

Experiment against prediction

8YC0 chain n against the predicted model P0CF51: TM-score 0.90, RMSD 0.59 Å
8WY0 chain n against the predicted model P0CF51: TM-score 0.90, RMSD 0.59 Å
8WYI chain n against the predicted model P0CF51: TM-score 0.86, RMSD 0.70 Å
8JC0 chain n against the predicted model P0CF51: TM-score 0.83, RMSD 0.99 Å
8YC0 chain n against the predicted model Q99603: TM-score 0.58, RMSD 1.75 Å
8WY0 chain n against the predicted model Q99603: TM-score 0.58, RMSD 1.74 Å
8JC0 chain n against the predicted model Q99603: TM-score 0.56, RMSD 2.51 Å
8WYI chain n against the predicted model Q99603: TM-score 0.55, RMSD 2.23 Å

Elsewhere

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