UniProt Q99459
Cell division cycle 5-like protein (Q99459)
Cell division cycle 5-like protein (UniProt Q99459): 27 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99459
- Protein
- Cell division cycle 5-like protein
- Experimental structures
- 27
- Predicted models
- 1
- Pockets
- 13 · 4 records with a druggable one
Structures
28 records of Q99459 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DIM | Solution structure of the Myb_DNA-binding domain of human Cell division cycle 5-like protein | solution nmr | A | — | — |
| 2DIM | Solution structure of the MYB_DNA-binding domain of human cell division cycle 5-like protein | solution nmr | A | — | — |
| 2DIN | Solution structure of the Myb_DNA-binding domain of human Cell division cycle 5-like protein | solution nmr | A | — | — |
| 2DIN | Solution structure of the MYB_DNA-binding domain of human cell division cycle 5-like protein | solution nmr | A | — | — |
| 5MQF | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | electron microscopy | L | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | L | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | L | — | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | L | — | 3 (best 0.84) |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | L | — | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | L | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | L | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9… | electron microscopy | L | — | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to PRP43 loaded (ILS1 complex) at 2.9… | electron microscopy | L | — | — |
| 6ID1 | Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex) at 2.9… | electron microscopy | L | — | — |
| 6ZYM | Human C Complex Spliceosome - High-resolution CORE | electron microscopy | L | — | 2 (best 0.82) |
| 6ZYM | Human C complex spliceosome - high-resolution core | electron microscopy | L | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | L | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | L | — | — |
| 7AAV | Human pre-bact-2 spliceosome core structure | electron microscopy | L | — | — |
| 7ABH | Human pre-bact-2 spliceosome (SF3B/U2 snrnp portion) | electron microscopy | L | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | L | — | — |
| 7DVQ | Cryo-EM structure of the activated human minor spliceosome (minor bact complex) | electron microscopy | L | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | L | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | L | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | L | — | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | O | — | 5 (best 0.91) |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | L | — | 3 (best 0.86) |
| Q99459 | AlphaFold monomer V2.0 prediction for cell division cycle 5-like protein (Q99459) | predicted | A | — | — |
Experiment against prediction
- 7DVQ chain L against the predicted model Q99459: TM-score 0.95, RMSD 0.86 Å
- 6FF4 chain L against the predicted model Q99459: TM-score 0.92, RMSD 1.06 Å
- 6FF4 chain L against the predicted model Q99459: TM-score 0.92, RMSD 1.06 Å
- 6FF7 chain L against the predicted model Q99459: TM-score 0.91, RMSD 1.12 Å
- 6ZYM chain L against the predicted model Q99459: TM-score 0.90, RMSD 2.00 Å
- 6ZYM chain L against the predicted model Q99459: TM-score 0.90, RMSD 2.00 Å
- 5Z58 chain L against the predicted model Q99459: TM-score 0.90, RMSD 1.74 Å
- 7AAV chain L against the predicted model Q99459: TM-score 0.90, RMSD 1.33 Å
- 7ABI chain L against the predicted model Q99459: TM-score 0.83, RMSD 1.01 Å
- 7ABH chain L against the predicted model Q99459: TM-score 0.81, RMSD 1.06 Å
Elsewhere
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