UniProt Q96WV5
Putative coatomer subunit alpha (Q96WV5)
Putative coatomer subunit alpha (UniProt Q96WV5): 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96WV5
- Protein
- Putative coatomer subunit alpha
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 39 · 7 records with a druggable one
Structures
17 records of Q96WV5 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4J87 | Crystal structure of alpha-COP | x-ray diffraction | A | — | — |
| 4J87 | Crystal structure of alpha-cop | x-ray diffraction | A | — | — |
| 4J8B | Crystal structure of alpha-COP/Emp47p complex | x-ray diffraction | A | — | — |
| 4J8B | Crystal structure of alpha-COP/EMP47P complex | x-ray diffraction | A | — | — |
| 4J8G | Crystal structure of alpha-COP/E19 complex | x-ray diffraction | A, B | — | — |
| 4J8G | Crystal structure of alpha-COP/E19 complex | x-ray diffraction | A, B | — | — |
| 7S16 | Crystal structure of alpha-COP-WD40 domain R57A mutant | x-ray diffraction | A | NA | 1 (best 0.82) |
| 7S16 | Crystal structure of alpha-cop-WD40 domain R57A mutant | x-ray diffraction | A | ACE | — |
| 7S22 | Crystal structure of alpha-COP-WD40 domain | x-ray diffraction | A, B, C | — | 7 (best 0.83) |
| 7S22 | Crystal structure of alpha-cop-WD40 domain | x-ray diffraction | A, B, C | ACE | — |
| 7S23 | Crystal structure of alpha-COP-WD40 domain, Y139A mutant | x-ray diffraction | A, B, C | — | 7 (best 0.82) |
| 7S23 | Crystal structure of alpha-cop-WD40 domain, Y139A mutant | x-ray diffraction | A, B, C | ACE | — |
| 8ENY | Crystal structure of alpha-COPI-WD40 domain R13A mutant. | x-ray diffraction | A, B, C | ACE | 6 (best 0.82) |
| 8ENZ | Crystal structure of alpha-COPI-WD40 domain K15A mutant. | x-ray diffraction | A, B, C | ACE | 7 (best 0.83) |
| 8EO0 | Crystal structure of alpha-COPI WD40 domain R300A mutant. | x-ray diffraction | A, B, C | ACE | 6 (best 0.82) |
| 8EVL | Crystal structure of alpha-COPI N-terminal WD40 domain | x-ray diffraction | A, B, C | — | 5 (best 0.83) |
| Q96WV5 | AlphaFold monomer V2.0 prediction for putative coatomer subunit alpha (Q96WV5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4J8G chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.56 Å
- 4J8G chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.56 Å
- 4J8B chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.69 Å
- 4J8B chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.69 Å
- 8EVL chain C against the predicted model Q96WV5: TM-score 0.99, RMSD 0.62 Å
- 8EVL chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.62 Å
- 8EVL chain B against the predicted model Q96WV5: TM-score 0.99, RMSD 0.61 Å
- 8EO0 chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.81 Å
- 8EO0 chain C against the predicted model Q96WV5: TM-score 0.99, RMSD 0.82 Å
- 8ENY chain A against the predicted model Q96WV5: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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