UniProt Q96RQ3
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (Q96RQ3)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (UniProt Q96RQ3), EC 6.4.1.4: 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 97 pockets. Binding sites, druggability and experiment…
- UniProt
- Q96RQ3
- Protein
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- EC
- 6.4.1.4
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 97 · 7 records with a druggable one
Structures
10 records of Q96RQ3 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EJM | Solution structure of RUH-072, an apo-biotnyl domain form human acetyl coenzyme A carboxylase | solution nmr | A | — | — |
| 2EJM | Solution structure of ruh-072, an apo-biotnyl domain form human acetyl coenzyme a carboxylase | solution nmr | A | — | — |
| 8J4Z | Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate | electron microscopy | E, B, D, G, I, L | BTI | 17 (best 0.80) |
| 8J78 | Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state | electron microscopy | I, K, C, B, E, G | BTI | 12 (best 0.85) |
| 8J7D | Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state | electron microscopy | A, D, F, H, I, L | BTI | 12 (best 0.86) |
| 8J99 | Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state | electron microscopy | A, C, E, F, I, K | — | 11 (best 0.76) |
| 8JAW | Human MCC in MCCD state | electron microscopy | A, C, E, F, H, K | BTI | 16 (best 0.86) |
| 8JXM | Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state with MCoA | electron microscopy | L, B, F, G, I, M | BTI | 12 (best 0.79) |
| 8XL6 | Structure of human 3-methylcrotonyl-CoA carboxylase at apo-state (MCC-Apo) | electron microscopy | A, C, E, G, I, K | BTN | 17 (best 0.82) |
| Q96RQ3 | AlphaFold monomer V2.0 prediction for methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8J99 chain F against the predicted model Q96RQ3: TM-score 0.96, RMSD 1.01 Å
- 8J99 chain K against the predicted model Q96RQ3: TM-score 0.95, RMSD 1.03 Å
- 8J99 chain A against the predicted model Q96RQ3: TM-score 0.95, RMSD 1.05 Å
- 8J99 chain I against the predicted model Q96RQ3: TM-score 0.95, RMSD 1.04 Å
- 8J99 chain E against the predicted model Q96RQ3: TM-score 0.95, RMSD 1.04 Å
- 8J99 chain C against the predicted model Q96RQ3: TM-score 0.95, RMSD 1.05 Å
- 8JXM chain M against the predicted model Q96RQ3: TM-score 0.94, RMSD 2.19 Å
- 8JXM chain G against the predicted model Q96RQ3: TM-score 0.94, RMSD 2.19 Å
- 8JXM chain F against the predicted model Q96RQ3: TM-score 0.94, RMSD 2.19 Å
- 8JXM chain I against the predicted model Q96RQ3: TM-score 0.94, RMSD 2.20 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.