UniProt Q96QB1
Rho GTPase-activating protein 7 (Q96QB1)
Rho GTPase-activating protein 7 (UniProt Q96QB1): 12 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96QB1
- Protein
- Rho GTPase-activating protein 7
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
13 records of Q96QB1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DKY | Solution structure of the SAM-domain of Rho-GTPase-activating protein 7 | solution nmr | A | — | — |
| 2DKY | Solution structure of the SAM-domain of rho-GTPase-activating protein 7 | solution nmr | A | — | — |
| 2GYT | Solution structure of the SAM (sterile alpha motif) domain of DLC1 (deleted in liver cancer 1) | solution nmr | A | — | — |
| 2GYT | Solution structure of the SAM (sterile alpha motif) domain of DLC1 (deleted in liver cancer 1) | solution nmr | A | — | — |
| 2KAP | Solution structure of DLC1-SAM | solution nmr | A | — | — |
| 2KAP | Solution structure of DLC1-SAM | solution nmr | A | — | — |
| 2LOZ | The novel binding mode of DLC1 and Tensin2 PTB domain | solution nmr | B | — | — |
| 2LOZ | The novel binding mode of DLC1 and TENSIN2 ptb domain | solution nmr | B | — | — |
| 3KUQ | Crystal structure of the DLC1 RhoGAP domain | x-ray diffraction | A | — | — |
| 3KUQ | Crystal structure of the DLC1 rhogap domain | x-ray diffraction | A | — | — |
| 5FZT | The crystal structure of R7R8 in complex with a DLC1 fragment. | x-ray diffraction | B | — | — |
| 5FZT | The crystal structure of R7R8 in complex with a DLC1 fragment. | x-ray diffraction | B | — | — |
| Q96QB1 | AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 7 (Q96QB1) | predicted | A | — | 13 (best 0.82) |
Experiment against prediction
- 3KUQ chain A against the predicted model Q96QB1: TM-score 0.95, RMSD 1.39 Å
- 3KUQ chain A against the predicted model Q96QB1: TM-score 0.95, RMSD 1.39 Å
- 2GYT chain A against the predicted model Q96QB1: TM-score 0.80, RMSD 1.88 Å
- 2GYT chain A against the predicted model Q96QB1: TM-score 0.80, RMSD 1.88 Å
- 2KAP chain A against the predicted model Q96QB1: TM-score 0.80, RMSD 1.56 Å
- 2KAP chain A against the predicted model Q96QB1: TM-score 0.80, RMSD 1.56 Å
- 2DKY chain A against the predicted model Q96QB1: TM-score 0.69, RMSD 1.38 Å
- 2DKY chain A against the predicted model Q96QB1: TM-score 0.69, RMSD 1.38 Å
- 5FZT chain B against the predicted model Q96QB1: TM-score 0.63, RMSD 0.72 Å
- 5FZT chain B against the predicted model Q96QB1: TM-score 0.63, RMSD 0.72 Å
Elsewhere
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