UniProt Q96NN9
Apoptosis-inducing factor 3 (Q96NN9)
Apoptosis-inducing factor 3 (UniProt Q96NN9), EC 1.-.-.-: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96NN9
- Protein
- Apoptosis-inducing factor 3
- EC
- 1.-.-.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 13 · 3 records with a druggable one
Structures
9 records of Q96NN9 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5O9V | HSNMT1 in complex with CoA and myristoylated-ggcfskpk octapeptide | x-ray diffraction | C, D | COA, MYR | — |
| 6QRM | HSNMT1 in complex with both myrcoa and gncfskrraa substrates | x-ray diffraction | C, D | COA, MYA, MYR | — |
| 6SJZ | HsNMT1 in complex with both MyrCoA and Acetylated-GNCFSKPR substrates | x-ray diffraction | E, F | MYA | 3 (best 0.76) |
| 6SJZ | HSNMT1 in complex with both myrcoa and acetylated-gncfskpr substrates | x-ray diffraction | E, F | ACE, MYA | — |
| 6SK2 | HsNMT1 in complex with both MyrCoA and Acetylated-GKSFSKPR peptide reveals N-terminal Lysine… | x-ray diffraction | D, F | COA, MYA, MYR | 4 (best 0.76) |
| 6SK2 | HSNMT1 in complex with both myrcoa and acetylated-gksfskpr peptide reveals N-terminal lysine… | x-ray diffraction | D, F | ACE, COA, MYA, MYR | — |
| 6SKJ | DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates | x-ray diffraction | C, D | COA, MYA, MYR | 6 (best 0.84) |
| 6SKJ | DELTAC2 C-terminal truncation of HSNMT1 in complex with myrcoa and gncfskpr substrates | x-ray diffraction | C, D | COA, MYA, MYR | — |
| Q96NN9 | AlphaFold monomer V2.0 prediction for apoptosis-inducing factor 3 (Q96NN9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6SKJ chain C against the predicted model Q96NN9: TM-score 0.57, RMSD 0.97 Å
- 6SKJ chain C against the predicted model Q96NN9: TM-score 0.57, RMSD 0.97 Å
- 6SKJ chain D against the predicted model Q96NN9: TM-score 0.55, RMSD 0.93 Å
- 6SKJ chain D against the predicted model Q96NN9: TM-score 0.55, RMSD 0.93 Å
- 6QRM chain C against the predicted model Q96NN9: TM-score 0.54, RMSD 0.77 Å
- 6SJZ chain E against the predicted model Q96NN9: TM-score 0.53, RMSD 1.11 Å
- 6SJZ chain E against the predicted model Q96NN9: TM-score 0.53, RMSD 1.11 Å
- 5O9V chain D against the predicted model Q96NN9: TM-score 0.51, RMSD 0.94 Å
- 6SK2 chain F against the predicted model Q96NN9: TM-score 0.51, RMSD 2.08 Å
- 6SK2 chain F against the predicted model Q96NN9: TM-score 0.51, RMSD 2.08 Å
Elsewhere
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