UniProt Q96L21
60S ribosomal protein L10-like (Q96L21)
60S ribosomal protein L10-like (UniProt Q96L21): 40 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96L21
- Protein
- 60S ribosomal protein L10-like
- Experimental structures
- 40
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 8 · 6 records with a druggable one
Structures
41 records of Q96L21 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UG0 | Structure of the human 80S ribosome | electron microscopy | LI | — | — |
| 4V6X | Structure of the human 80S ribosome | electron microscopy | CI | — | — |
| 5LKS | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | electron microscopy | LI | MG | — |
| 6IP5 | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | electron microscopy | 2D | — | 1 (best 0.89) |
| 6IP6 | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | electron microscopy | 2D | — | 1 (best 0.87) |
| 6IP8 | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | electron microscopy | 2D | — | — |
| 6LQM | Cryo-EM structure of a pre-60S ribosomal subunit - state C | electron microscopy | J | — | — |
| 6QZP | High-resolution cryo-EM structure of the human 80S ribosome | electron microscopy | LI | MG | — |
| 6XA1 | Structure of a drug-like compound stalled human translation termination complex | electron microscopy | LI | — | — |
| 6Y0G | Structure of human ribosome in classical-PRE state | electron microscopy | LI | MG | 1 (best 0.89) |
| 6Y2L | Structure of human ribosome in POST state | electron microscopy | LI | MG | — |
| 6Y57 | Structure of human ribosome in hybrid-PRE state | electron microscopy | LI | — | — |
| 6Y6X | Tetracenomycin X bound to the human ribosome | electron microscopy | LI | MG | — |
| 6Z6L | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | electron microscopy | LI | MG | — |
| 6Z6M | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | electron microscopy | LI | MG | — |
| 6Z6N | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | electron microscopy | LI | MG | 1 (best 0.89) |
| 6ZM7 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | electron microscopy | LI | MG | — |
| 6ZME | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | electron microscopy | LI | MG | — |
| 6ZMI | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | electron microscopy | LI | MG | — |
| 6ZMO | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | electron microscopy | LI | MG | — |
| 7BHP | Cryo-EM structure of the human Ebp1 - 80S ribosome | electron microscopy | LI | MG | — |
| 7OW7 | EIF6-bound large subunit of the human ribosome | electron microscopy | p | K | — |
| 7QVP | Human collided disome (di-ribosome) stalled on XBP1 mRNA | electron microscopy | LI, MI | — | — |
| 8IFD | Dibekacin-added human 80S ribosome | electron microscopy | 2D | MG | — |
| 8IFE | Arbekacin-added human 80S ribosome | electron microscopy | 2D | MG, 84G | — |
| 8JDJ | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | electron microscopy | O | MG | — |
| 8JDK | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | electron microscopy | O | MG | — |
| 8JDL | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated… | electron microscopy | O | MG | — |
| 8JDM | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated… | electron microscopy | O | MG | — |
| 8OHD | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) | electron microscopy | LI | MG | — |
| 8OJ0 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | electron microscopy | LI | MG | — |
| 8OJ5 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | electron microscopy | LI | MG | 1 (best 0.85) |
| 8OJ8 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | electron microscopy | LI | MG | — |
| 8QOI | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical… | electron microscopy | LI | MG, K | 1 (best 0.89) |
| 8QYX | Human 60S ribosomal subunit | electron microscopy | D1 | MG | — |
| 8UKB | In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome | electron microscopy | LI | MG | — |
| 8XSX | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | electron microscopy | LI | MG | — |
| 8Y0W | dormant ribosome with eIF5A, eEF2 and SERBP1 | electron microscopy | LI | MG | — |
| 8Y0X | Dormant ribosome with SERBP1 | electron microscopy | LI | MG | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | LI | — | — |
| Q96L21 | AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10-like (Q96L21) | predicted | A | — | 2 (best 0.41) |
Ligands
Experiment against prediction
- 8OJ5 chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.58 Å
- 8OHD chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.59 Å
- 8XSX chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.59 Å
- 8OJ8 chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.59 Å
- 8OJ0 chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.59 Å
- 6Y6X chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.60 Å
- 6Z6N chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.60 Å
- 6Z6M chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.59 Å
- 8Y0X chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.61 Å
- 7QVP chain LI against the predicted model Q96L21: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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