UniProt Q96IJ6
Mannose-1-phosphate guanyltransferase alpha (Q96IJ6)
Mannose-1-phosphate guanyltransferase alpha (UniProt Q96IJ6): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q96IJ6
- Protein
- Mannose-1-phosphate guanyltransferase alpha
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 33 · 3 records with a druggable one
Structures
7 records of Q96IJ6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7D72 | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | electron microscopy | A, B, C, D | GDD | 8 (best 0.79) |
| 7D72 | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-mannose | electron microscopy | A, B, C, D | GDD | — |
| 7D73 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | electron microscopy | A, B, C, D | GDD, GTP | 12 (best 0.78) |
| 7D73 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state I) | electron microscopy | A, B, C, D | GDD, GTP | — |
| 7D74 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | electron microscopy | A, D, B, C | GTP | 13 (best 0.76) |
| 7D74 | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | electron microscopy | A, D, B, C | GTP | — |
| Q96IJ6 | AlphaFold monomer V2.0 prediction for mannose-1-phosphate guanyltransferase alpha (Q96IJ6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7D73 chain C against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.05 Å
- 7D73 chain C against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.05 Å
- 7D73 chain A against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.07 Å
- 7D73 chain A against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.07 Å
- 7D72 chain C against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.10 Å
- 7D72 chain C against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.10 Å
- 7D72 chain A against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.11 Å
- 7D72 chain A against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.11 Å
- 7D74 chain D against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.32 Å
- 7D74 chain D against the predicted model Q96IJ6: TM-score 0.98, RMSD 1.32 Å
Elsewhere
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