UniProt Q969T7
7-methylguanosine phosphate-specific 5'-nucleotidase (Q969T7)
7-methylguanosine phosphate-specific 5'-nucleotidase (UniProt Q969T7), EC 3.1.3.5, 3.1.3.91: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 9 pockets. Binding sites, druggability and experiment…
- UniProt
- Q969T7
- Protein
- 7-methylguanosine phosphate-specific 5'-nucleotidase
- EC
- 3.1.3.5, 3.1.3.91
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 9 · 1 record with a druggable one
Structures
5 records of Q969T7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ZEE | Human cytosolic 5' nucleotidase iiib | x-ray diffraction | A | MG | — |
| 7ZEG | Human cytosolic 5' nucleotidase iiib in complex with 3,4-dif-BN7GMP | x-ray diffraction | A, B | IOO, MG | — |
| 7ZEH | Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7Guanine | x-ray diffraction | A, B, C, D | IPQ, RBL, MG, PO4, SO4 | 9 (best 0.73) |
| 7ZEH | Human cytosolic 5' nucleotidase iiib in complex with 3,4-dif- BN7GUANINE | x-ray diffraction | A, B, C, D | IPQ, RBL, MG, PO4, SO4 | — |
| Q969T7 | AlphaFold monomer V2.0 prediction for 7-methylguanosine phosphate- specific 5'-nucleotidase (Q969T7) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7ZEH chain B against the predicted model Q969T7: TM-score 0.96, RMSD 1.25 Å
- 7ZEH chain B against the predicted model Q969T7: TM-score 0.96, RMSD 1.25 Å
- 7ZEH chain A against the predicted model Q969T7: TM-score 0.96, RMSD 1.27 Å
- 7ZEH chain A against the predicted model Q969T7: TM-score 0.96, RMSD 1.27 Å
- 7ZEG chain B against the predicted model Q969T7: TM-score 0.96, RMSD 1.36 Å
- 7ZEG chain A against the predicted model Q969T7: TM-score 0.95, RMSD 1.55 Å
- 7ZEH chain C against the predicted model Q969T7: TM-score 0.95, RMSD 1.52 Å
- 7ZEH chain C against the predicted model Q969T7: TM-score 0.95, RMSD 1.52 Å
- 7ZEH chain D against the predicted model Q969T7: TM-score 0.95, RMSD 1.56 Å
- 7ZEH chain D against the predicted model Q969T7: TM-score 0.95, RMSD 1.56 Å
Elsewhere
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