UniProt Q969Q1
E3 ubiquitin-protein ligase TRIM63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (UniProt Q969Q1), EC 6.3.2.-: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q969Q1
- Protein
- E3 ubiquitin-protein ligase TRIM63
- EC
- 6.3.2.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
7 records of Q969Q1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2D8U | Solution structure of the B-box domain of the human tripartite motif-containing 63 protein | solution nmr | A | — | — |
| 2D8U | Solution structure of the B-box domain of the human tripartite motif- containing 63 protein | solution nmr | A | ZN | — |
| 3DDT | Crystal structure of the B2 box from MuRF1 in dimeric state | x-ray diffraction | A, B, C | ZN | 3 (best 0.58) |
| 3DDT | Crystal structure of the B2 box from MURF1 in dimeric state | x-ray diffraction | A, B, C | — | — |
| 4M3L | Crystal Structure of the coiled coil domain of MuRF1 | x-ray diffraction | A, C, B, D | — | — |
| 4M3L | Crystal structure of the coiled coil domain of MURF1 | x-ray diffraction | A, C, B, D | — | — |
| Q969Q1 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM63 (Q969Q1) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 4M3L chain B against the predicted model Q969Q1: TM-score 0.94, RMSD 0.67 Å
- 4M3L chain B against the predicted model Q969Q1: TM-score 0.94, RMSD 0.67 Å
- 3DDT chain C against the predicted model Q969Q1: TM-score 0.92, RMSD 1.32 Å
- 3DDT chain C against the predicted model Q969Q1: TM-score 0.92, RMSD 1.32 Å
- 4M3L chain C against the predicted model Q969Q1: TM-score 0.90, RMSD 1.00 Å
- 4M3L chain C against the predicted model Q969Q1: TM-score 0.90, RMSD 1.00 Å
- 4M3L chain D against the predicted model Q969Q1: TM-score 0.88, RMSD 0.91 Å
- 4M3L chain D against the predicted model Q969Q1: TM-score 0.88, RMSD 0.91 Å
- 3DDT chain B against the predicted model Q969Q1: TM-score 0.88, RMSD 1.73 Å
- 3DDT chain B against the predicted model Q969Q1: TM-score 0.88, RMSD 1.73 Å
Elsewhere
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