UniProt Q93063
Exostosin-2 (Q93063)
Exostosin-2 (UniProt Q93063), EC 2.4.1.224, 2.4.1.225: 2 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q93063
- Protein
- Exostosin-2
- EC
- 2.4.1.224, 2.4.1.225
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 25 · 2 records with a druggable one
Structures
3 records of Q93063 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SCK | Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with a 7-sugar… | electron microscopy | B | NAG, BMA, NDG, BDP, UDP, MN | 12 (best 0.88) |
| 7UQY | Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer in complex with UDP-GlcA | electron microscopy | B | NAG, BMA | 13 (best 0.89) |
| Q93063 | AlphaFold monomer V2.0 prediction for exostosin-2 (Q93063) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UQY chain B against the predicted model Q93063: TM-score 0.66, RMSD 4.51 Å
- 7SCK chain B against the predicted model Q93063: TM-score 0.63, RMSD 4.91 Å
Elsewhere
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