UniProt Q92947
Glutaryl-CoA dehydrogenase (Q92947)
Glutaryl-CoA dehydrogenase (UniProt Q92947), EC 1.3.99.7: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92947
- Protein
- Glutaryl-CoA dehydrogenase
- EC
- 1.3.99.7
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
9 records of Q92947 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SIQ | The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase | x-ray diffraction | A | FAD | 3 (best 0.72) |
| 1SIQ | The crystal structure and mechanism of human glutaryl-CoA dehydrogenase | x-ray diffraction | A | — | — |
| 1SIR | The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase | x-ray diffraction | A | FAD, NBC | 3 (best 0.71) |
| 1SIR | The crystal structure and mechanism of human glutaryl-CoA dehydrogenase | x-ray diffraction | A | — | — |
| 2R0M | The effect of a Glu370Asp Mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the… | x-ray diffraction | A | — | — |
| 2R0M | The effect of a GLU370ASP mutation in glutaryl-CoA dehydrogenase on proton transfer to the… | x-ray diffraction | A | — | — |
| 2R0N | The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the… | x-ray diffraction | A | — | — |
| 2R0N | The effect of a GLU370ASP mutation in glutaryl-CoA dehydrogenase on proton transfer to the… | x-ray diffraction | A | — | — |
| Q92947 | AlphaFold monomer V2.0 prediction for glutaryl-CoA dehydrogenase, mitochondrial (Q92947) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1SIQ chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.22 Å
- 1SIQ chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.22 Å
- 1SIR chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.24 Å
- 1SIR chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.24 Å
- 2R0M chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.29 Å
- 2R0M chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.29 Å
- 2R0N chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.33 Å
- 2R0N chain A against the predicted model Q92947: TM-score 1.00, RMSD 0.33 Å
Elsewhere
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