UniProt Q92887
ATP-binding cassette sub-family C member 2 (Q92887)
ATP-binding cassette sub-family C member 2 (UniProt Q92887), EC 7.6.2.-, 7.6.2.2: 8 experimental structures on GenesisL1, 6 ligands bound, 137 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q92887
- Protein
- ATP-binding cassette sub-family C member 2
- EC
- 7.6.2.-, 7.6.2.2, 7.6.2.3
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 137 · 7 records with a druggable one
Structures
8 records of Q92887 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8IZR | Multidrug resistance-associated protein 3 | electron microscopy | A | — | 20 (best 0.83) |
| 8JX7 | Cryo-EM structure of human ABC transporter ABCC2 | electron microscopy | A | — | 20 (best 0.89) |
| 8JXQ | Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2 | electron microscopy | A | CLR, FEI | 17 (best 0.85) |
| 8JXU | Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition | electron microscopy | A | ADP, ATP, MG | 20 (best 0.89) |
| 8JY5 | Cryo-EM structure of human ABC transporter ABCC2 in apo state" | electron microscopy | A | — | 20 (best 0.89) |
| 9BR2 | Inward-facing, ATP-bound Multidrug Resistance-associated Protein 2 (MRP2) (E1462Q) | electron microscopy | A | ATP, MG, UNL, CLR | 20 (best 0.90) |
| 9BUK | Outward-facing, ATP-bound Multidrug Resistance-associated Protein 2 (MRP2) (E1462Q) | electron microscopy | A | ATP, MG, UNL, CLR | 20 (best 0.87) |
| Q92887 | AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 2 (Q92887) | — | — | — |
Ligands
- ATP · Adenosine-5'-triphosphate · in 3 records
- CLR · Cholesterol · in 3 records
- MG · Magnesium ion · in 3 records
- UNL · Unknown ligand · in 2 records
- ADP · Adenosine-5'-diphosphate · in 1 record
- FEI · 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid · in 1 record
Elsewhere
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