UniProt Q92841
Probable ATP-dependent RNA helicase DDX17 (Q92841)
Probable ATP-dependent RNA helicase DDX17 (UniProt Q92841), EC 3.6.4.13: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q92841
- Protein
- Probable ATP-dependent RNA helicase DDX17
- EC
- 3.6.4.13
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 28 · 5 records with a druggable one
Structures
11 records of Q92841 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6UV0 | Crystal structure of apo core domain of RNA helicase DDX17 | x-ray diffraction | A, B | MG | 11 (best 0.64) |
| 6UV0 | Crystal structure of apo core domain of RNA helicase DDX17 | x-ray diffraction | A, B | MG | — |
| 6UV1 | Crystal structure of RNA helicase DDX17 in complex of rU10 RNA | x-ray diffraction | A, B | ADP, BEF, MG | 6 (best 0.71) |
| 6UV1 | Crystal structure of RNA helicase DDX17 in complex of RU10 RNA | x-ray diffraction | A, B | ADP, BEF, MG | — |
| 6UV2 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo1 | x-ray diffraction | A | ADP, BEF, MG | 3 (best 0.64) |
| 6UV2 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125A-OLIGO1 | x-ray diffraction | A | ADP, BEF, MG | — |
| 6UV3 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo2 | x-ray diffraction | A | ADP, BEF, MG | 3 (best 0.65) |
| 6UV3 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125A-OLIGO2 | x-ray diffraction | A | ADP, BEF, MG | — |
| 6UV4 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18a-oligo1 | x-ray diffraction | A | ADP, BEF, MG | 5 (best 0.66) |
| 6UV4 | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18A-OLIGO1 | x-ray diffraction | A | ADP, BEF, MG | — |
| Q92841 | AlphaFold monomer V2.0 prediction for probable ATP-dependent RNA helicase DDX17 (Q92841) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6UV2 chain A against the predicted model Q92841: TM-score 1.00, RMSD 0.52 Å
- 6UV2 chain A against the predicted model Q92841: TM-score 1.00, RMSD 0.52 Å
- 6UV3 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.57 Å
- 6UV3 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.57 Å
- 6UV1 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.64 Å
- 6UV1 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.64 Å
- 6UV1 chain B against the predicted model Q92841: TM-score 0.99, RMSD 0.65 Å
- 6UV1 chain B against the predicted model Q92841: TM-score 0.99, RMSD 0.65 Å
- 6UV4 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.73 Å
- 6UV4 chain A against the predicted model Q92841: TM-score 0.99, RMSD 0.73 Å
Elsewhere
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