UniProt Q92835
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (Q92835)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (UniProt Q92835), EC 3.1.3.36, 3.1.3.56: 127 experimental structures on GenesisL1, 99 ligands bound, 124 pockets. Binding sites, pockets, druggability and 3D structures in…
- UniProt
- Q92835
- Protein
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
- EC
- 3.1.3.36, 3.1.3.56, 3.1.3.86
- Experimental structures
- 127
- Predicted models
- 0
- Ligands
- 99
- Pockets
- 124 · 27 records with a druggable one
Structures
127 records of Q92835 in the MolNFT archive: 127 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5RW2 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | T0V | — |
| 5RW2 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | T0V | — |
| 5RW3 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLY | 5 (best 0.67) |
| 5RW3 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLY | — |
| 5RW4 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLV | 4 (best 0.68) |
| 5RW4 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLV | — |
| 5RW5 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMV | — |
| 5RW6 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLS | 4 (best 0.67) |
| 5RW6 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WLS | — |
| 5RW7 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMY | — |
| 5RW8 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WN1 | — |
| 5RW9 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | QKZ, PO4 | 5 (best 0.68) |
| 5RW9 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | QKZ, PO4 | — |
| 5RWA | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | O3M | 5 (best 0.68) |
| 5RWA | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | O3M | — |
| 5RWB | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | T0Y | 5 (best 0.68) |
| 5RWB | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | T0Y | — |
| 5RWC | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | 2L1 | — |
| 5RWD | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NUJ | 4 (best 0.67) |
| 5RWD | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NUJ | — |
| 5RWE | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | JJG | 5 (best 0.68) |
| 5RWE | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | JJG | — |
| 5RWF | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMS | — |
| 5RWF | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMS | — |
| 5RWG | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | S07 | — |
| 5RWG | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | S07 | — |
| 5RWH | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | VZM | — |
| 5RWI | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | O3D | 5 (best 0.68) |
| 5RWI | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | O3D | — |
| 5RWJ | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | AXS, PO4 | — |
| 5RWK | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WN4 | 4 (best 0.68) |
| 5RWK | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WN4 | — |
| 5RWL | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NTG | 5 (best 0.68) |
| 5RWL | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NTG | — |
| 5RWM | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NU4 | — |
| 5RWN | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | U0V | 5 (best 0.68) |
| 5RWN | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | U0V | — |
| 5RWO | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | AXG | — |
| 5RWO | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | AXG | — |
| 5RWP | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | JO1 | — |
| 5RWQ | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | K0G | — |
| 5RWR | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | O3G | — |
| 5RWS | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WN7, PO4 | — |
| 5RWS | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WN7, PO4 | — |
| 5RWT | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | JMM | 5 (best 0.67) |
| 5RWT | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | JMM | — |
| 5RWU | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WNA | — |
| 5RWV | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WND | 5 (best 0.67) |
| 5RWV | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WND | — |
| 5RWW | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NV7 | 5 (best 0.67) |
| 5RWW | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NV7 | — |
| 5RWX | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | K0V | 5 (best 0.67) |
| 5RWX | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | K0V | — |
| 5RWY | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | RWV | — |
| 5RWZ | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WNG | 5 (best 0.67) |
| 5RWZ | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WNG | — |
| 5RX0 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | NVD, PO4, MG | — |
| 5RX1 | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMG, WMD | 4 (best 0.68) |
| 5RX1 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WMG, WMD | — |
| 5RX2 | INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2 domains of… | x-ray diffraction | A | WP4, WM7 | — |
67 records more on the page itself.
Ligands
- PO4 · Phosphate ion · in 9 records
- AXG · 1-(phenylmethyl)-4-pyrrol-1-yl-piperidine · in 2 records
- B1J · [1-(4-chlorophenyl)-1,2,3-triazol-4-yl]methanol · in 2 records
- JJG · 4-[2-(phenylsulfanyl)ethyl]morpholine · in 2 records
- JMM · [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl) methanone · in 2 records
- K0V · methyl 1-(tert-butylcarbamoyl)piperidine-4-carboxylate · in 2 records
- MN · Manganese (II) ion · in 2 records
- NTG · 5-(1,4-oxazepan-4-yl)pyridine-2-carbonitrile · in 2 records
- NUJ · trans-3-[(2,6-dimethylpyrimidin-4-yl)(methyl)amino]cyclobutan-1-ol · in 2 records
- NV7 · 1-[(furan-2-yl)methyl]-4-(methylsulfonyl)piperazine · in 2 records
- O0P · N-[(3-fluorophenyl)methyl]-N-methylsulfuric diamide · in 2 records
- O3D · 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione · in 2 records
- O3M · 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol · in 2 records
- QKZ · 2-(4-chlorophenyl)-~{N}-pyrimidin-2-yl-ethanamide · in 2 records
- RX7 · 2-methyl-2-{[(3-methylthiophen-2-yl) methyl]amino}propan-1-ol · in 2 records
- S07 · 2-(2,4-dimethylphenoxy)-1-morpholin-4-yl-ethanone · in 2 records
- T0V · 1-(3-fluorophenyl)-N-[(furan-2-yl)methyl]methanamine · in 2 records
- T0Y · 1-[(thiophen-3-yl)methyl]piperidin-4-ol · in 2 records
- U0V · 2-fluoro-N-[2-(pyridin-4-yl)ethyl]benzamide · in 2 records
- UWV · 2-fluoro-N-[(1H-pyrazol-3-yl)methyl]aniline · in 2 records
- WK4 · 2-(1H-imidazol-1-yl)ethyl dimethylcarbamate · in 2 records
- WK7 · 3-fluoro-4-(piperazin-1-yl)benzonitrile · in 2 records
- WKA · N-(2,1,3-benzoxadiazol-4-yl)acetamide · in 2 records
- WKP · (4-methoxyphenyl)(piperidin-4-yl)methanone · in 2 records
- WLS · 1-(pyridin-4-yl)-N-[(thiophen-2-yl)methyl]methanamine · in 2 records
- WLV · N-(3-fluorophenyl)-2-phenoxyacetamide · in 2 records
- WLY · 2-(4-methylphenyl)-N-{[(2S)-oxolan-2-yl]methyl}acetamide · in 2 records
- WMD · 1-[(1R)-1-(2-fluorophenyl)ethyl]piperazine · in 2 records
- WMG · 1-[(1S)-1-(2-fluorophenyl)ethyl]piperazine · in 2 records
- WMS · 5-fluoro-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyridin-3-amine · in 2 records
Elsewhere
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