UniProt Q92729
Receptor-type tyrosine-protein phosphatase U (Q92729)
Receptor-type tyrosine-protein phosphatase U (UniProt Q92729), EC 3.1.3.48: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q92729
- Protein
- Receptor-type tyrosine-protein phosphatase U
- EC
- 3.1.3.48
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 2 records with a druggable one
Structures
5 records of Q92729 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SUB | Human PTPRU D1 domain, reduced form | x-ray diffraction | A | CL | 3 (best 0.52) |
| 6SUB | Human ptpru D1 domain, reduced form | x-ray diffraction | A | CL | — |
| 6SUC | Human PTPRU D1 domain, oxidised form | x-ray diffraction | A | — | 3 (best 0.35) |
| 6SUC | Human ptpru D1 domain, oxidised form | x-ray diffraction | A | — | — |
| Q92729 | AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase U (Q92729) | predicted | A | — | 11 (best 0.77) |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 6SUC chain A against the predicted model Q92729: TM-score 0.97, RMSD 1.07 Å
- 6SUC chain A against the predicted model Q92729: TM-score 0.97, RMSD 1.07 Å
- 6SUB chain A against the predicted model Q92729: TM-score 0.97, RMSD 1.31 Å
- 6SUB chain A against the predicted model Q92729: TM-score 0.97, RMSD 1.31 Å
Elsewhere
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