UniProt Q922S8
Kinesin-like protein KIF2C (Q922S8)
Kinesin-like protein KIF2C (UniProt Q922S8): 9 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q922S8
- Protein
- Kinesin-like protein KIF2C
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 14 · 1 record with a druggable one
Structures
10 records of Q922S8 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1V8J | The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C… | x-ray diffraction | A | — | — |
| 1V8J | The crystal structure of the minimal functional domain of the microtubule destabilizer KIF2C… | x-ray diffraction | A | — | — |
| 1V8K | The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C… | x-ray diffraction | A | — | — |
| 1V8K | The crystal structure of the minimal functional domain of the microtubule destabilizer KIF2C… | x-ray diffraction | A | — | — |
| 3EDL | Kinesin13-Microtubule Ring complex | electron microscopy | D | — | — |
| 3EDL | KINESIN13-microtubule ring complex | electron microscopy | D | — | — |
| 5XJA | The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed… | x-ray diffraction | A, B | MG, ADP, AF3 | 14 (best 0.75) |
| 5XJA | The crystal structure of the minimal core domain of the microtubule depolymerizer KIF2C complexed… | x-ray diffraction | A, B | MG, ADP, AF3 | — |
| 5XJB | The crystal structure of the minimal core domain of the microtubule depolymerizer KIF2C complexed… | x-ray diffraction | A, B | ADP, BEF, MG | — |
| Q922S8 | AlphaFold monomer V2.0 prediction for kinesin-like protein KIF2C (Q922S8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3EDL chain D against the predicted model Q922S8: TM-score 0.98, RMSD 1.01 Å
- 3EDL chain D against the predicted model Q922S8: TM-score 0.98, RMSD 1.01 Å
- 1V8J chain A against the predicted model Q922S8: TM-score 0.92, RMSD 1.64 Å
- 1V8J chain A against the predicted model Q922S8: TM-score 0.92, RMSD 1.64 Å
- 5XJB chain B against the predicted model Q922S8: TM-score 0.91, RMSD 1.21 Å
- 5XJA chain B against the predicted model Q922S8: TM-score 0.91, RMSD 1.22 Å
- 5XJA chain B against the predicted model Q922S8: TM-score 0.91, RMSD 1.22 Å
- 5XJA chain A against the predicted model Q922S8: TM-score 0.91, RMSD 1.45 Å
- 5XJA chain A against the predicted model Q922S8: TM-score 0.91, RMSD 1.45 Å
- 1V8K chain A against the predicted model Q922S8: TM-score 0.91, RMSD 1.26 Å
Elsewhere
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