UniProt Q8WYH8
Inhibitor of growth protein 5 (Q8WYH8)
Inhibitor of growth protein 5 (UniProt Q8WYH8): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8WYH8
- Protein
- Inhibitor of growth protein 5
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 2 records with a druggable one
Structures
7 records of Q8WYH8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3C6W | Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide | x-ray diffraction | A, C | — | — |
| 3C6W | Crystal structure of the ING5 phd finger in complex with H3K4ME3 peptide | x-ray diffraction | A, C | — | — |
| 5ME8 | N-terminal domain of the human tumor suppressor ING5 | x-ray diffraction | A, B | — | 2 (best 0.50) |
| 5ME8 | N-terminal domain of the human tumor suppressor ING5 | x-ray diffraction | A, B | — | — |
| 5MTO | N-terminal domain of the human tumor suppressor ING5 C19S mutant | x-ray diffraction | A, B | NA, SO4 | 3 (best 0.52) |
| 5MTO | N-terminal domain of the human tumor suppressor ING5 C19S mutant | x-ray diffraction | A, B | NA, SO4 | — |
| Q8WYH8 | AlphaFold monomer V2.0 prediction for inhibitor of growth protein 5 (Q8WYH8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3C6W chain A against the predicted model Q8WYH8: TM-score 0.97, RMSD 0.42 Å
- 3C6W chain A against the predicted model Q8WYH8: TM-score 0.97, RMSD 0.42 Å
- 3C6W chain C against the predicted model Q8WYH8: TM-score 0.95, RMSD 0.56 Å
- 3C6W chain C against the predicted model Q8WYH8: TM-score 0.95, RMSD 0.56 Å
- 5ME8 chain A against the predicted model Q8WYH8: TM-score 0.76, RMSD 1.59 Å
- 5ME8 chain A against the predicted model Q8WYH8: TM-score 0.76, RMSD 1.59 Å
- 5MTO chain A against the predicted model Q8WYH8: TM-score 0.72, RMSD 1.94 Å
- 5MTO chain A against the predicted model Q8WYH8: TM-score 0.72, RMSD 1.94 Å
- 5ME8 chain B against the predicted model Q8WYH8: TM-score 0.71, RMSD 1.71 Å
Elsewhere
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