UniProt Q8WXI7
Mucin-16 (Q8WXI7)
Mucin-16 (UniProt Q8WXI7): 5 experimental structures on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8WXI7
- Protein
- Mucin-16
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 14 · 2 records with a druggable one
Structures
5 records of Q8WXI7 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SA9 | Human MUC16 SEA5 Domain | x-ray diffraction | A, B | — | 1 (best 0.57) |
| 7SA9 | Human MUC16 SEA5 domain | x-ray diffraction | A, B | — | — |
| 8GKL | Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6 | x-ray diffraction | E | — | 2 (best 0.47) |
| 8VM1 | Structural Elucidation of the Mesothelin Mucin16 CA125 Interaction | x-ray diffraction | A | NAG | 1 (best 0.41) |
| 8VRS | Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody | x-ray diffraction | A, B | — | 10 (best 0.79) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 8VRS chain B against the predicted model P0AEX9: TM-score 0.94, RMSD 0.71 Å
- 8VRS chain A against the predicted model P0AEX9: TM-score 0.94, RMSD 0.76 Å
- 8VM1 chain A against the predicted model Q13421: TM-score 0.44, RMSD 3.99 Å
Elsewhere
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