UniProt Q8WV22
Non-structural maintenance of chromosomes element 1 homolog (Q8WV22)
Non-structural maintenance of chromosomes element 1 homolog (UniProt Q8WV22), EC 6.3.2.-: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8WV22
- Protein
- Non-structural maintenance of chromosomes element 1 homolog
- EC
- 6.3.2.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
7 records of Q8WV22 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CT0 | Solution structure of the RING domain of the Non-SMC element 1 protein | solution nmr | A | — | — |
| 2CT0 | Solution structure of the ring domain of the non-smc element 1 protein | solution nmr | A | — | — |
| 5HVQ | Alternative model of the MAGE-G1 NSE-1 complex | x-ray diffraction | C | ZN | 2 (best 0.74) |
| 5HVQ | Alternative model of the mage-G1 nse-1 complex | x-ray diffraction | C | — | — |
| 5WY5 | Crystal structure of MAGEG1 and NSE1 complex | x-ray diffraction | A | ZN | 3 (best 0.70) |
| 5WY5 | Crystal structure of MAGEG1 and NSE1 complex | x-ray diffraction | A | ZN | — |
| Q8WV22 | AlphaFold monomer V2.0 prediction for non-structural maintenance of chromosomes element 1 homolog… | predicted | A | — | 2 (best 0.46) |
Ligands
- ZN · Zinc ion · in 3 records
Experiment against prediction
- 5HVQ chain C against the predicted model Q8WV22: TM-score 1.00, RMSD 0.40 Å
- 5HVQ chain C against the predicted model Q8WV22: TM-score 1.00, RMSD 0.40 Å
- 5WY5 chain A against the predicted model Q8WV22: TM-score 0.99, RMSD 0.45 Å
- 5WY5 chain A against the predicted model Q8WV22: TM-score 0.99, RMSD 0.45 Å
- 2CT0 chain A against the predicted model Q8WV22: TM-score 0.74, RMSD 1.99 Å
- 2CT0 chain A against the predicted model Q8WV22: TM-score 0.74, RMSD 1.99 Å
Elsewhere
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