UniProt Q8TWG5
Malate dehydrogenase (Q8TWG5)
Malate dehydrogenase (UniProt Q8TWG5), EC 1.1.1.299: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TWG5
- Protein
- Malate dehydrogenase
- EC
- 1.1.1.299
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 22 · 3 records with a druggable one
Structures
3 records of Q8TWG5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8RS5 | Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 4 | x-ray diffraction | A, B | NDP, CL, K | 10 (best 0.65) |
| 8RWL | Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 1 | x-ray diffraction | A, B | NDP, CL, NA | 9 (best 0.68) |
| Q8TWG5 | AlphaFold monomer V2.0 prediction for malate dehydrogenase (Q8TWG5) | predicted | A | — | 3 (best 0.71) |
Ligands
Experiment against prediction
- 8RWL chain A against the predicted model Q8TWG5: TM-score 0.99, RMSD 0.62 Å
- 8RWL chain B against the predicted model Q8TWG5: TM-score 0.99, RMSD 0.64 Å
- 8RS5 chain B against the predicted model Q8TWG5: TM-score 0.98, RMSD 0.90 Å
- 8RS5 chain A against the predicted model Q8TWG5: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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